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Titlebook: Major Histocompatibility Complex; Evolution, Structure Masanori Kasahara (Professor) Conference proceedings 2000 Springer Japan 2000 AIDS.A

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發(fā)表于 2025-3-21 16:10:50 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Major Histocompatibility Complex
副標(biāo)題Evolution, Structure
編輯Masanori Kasahara (Professor)
視頻videohttp://file.papertrans.cn/622/621568/621568.mp4
概述Updated information on MHC genetics and evolution
圖書(shū)封面Titlebook: Major Histocompatibility Complex; Evolution, Structure Masanori Kasahara (Professor) Conference proceedings 2000 Springer Japan 2000 AIDS.A
描述Every biological system is the outcome of evolution and has a history all its own. This history dictates how the system works and why it has certain properties and not others. This is why we need to study not only the structure and function, but also the history of the system. This argument undoubtedly applies to the study of the immune system and also to the study of the major histocompatibility complex (MHC). Since 1989, researchers of various scientific disciplines who share a deep inter- est in MHC evolution have held a meeting every two years to discuss their latest research developments, exchange ideas, and foster friendship. Together with my colleagues Drs. Naoyuki Takahata and Yoko Satta, I organized the Sixth Interna- tional Workshop on MHC Evolution in Hayama, Japan, May 25-29, 1999. This volume is the proceedings of that conference. It covers diverse topics pertinent to MHC evolution, including the origin of the adaptive immune system, the organi- zation of the MHC in humans and other model vertebrates, MHC-parasite co- evolution, and the nature and origin of MHC polymorphism. I hope that this book will be of interest not only for MHC researchers and immunologists, but a
出版日期Conference proceedings 2000
關(guān)鍵詞AIDS; Antigen; Immune System; Immunity; Viruses; proteins; regulation
版次1
doihttps://doi.org/10.1007/978-4-431-65868-9
isbn_softcover978-4-431-65870-2
isbn_ebook978-4-431-65868-9
copyrightSpringer Japan 2000
The information of publication is updating

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發(fā)表于 2025-3-21 21:40:04 | 只看該作者
The MHC paralogous group: listing of members and a brief overview of gene families with copies in the MHC and these paralogous regions has been increasing steadily and now counts 37. There are at least 50 gene families that do not have copies in the MHC but share paralogous copies among the paralogous regions on chromosomes 1, 9, and 19, or between two of them. T
板凳
發(fā)表于 2025-3-22 03:20:16 | 只看該作者
Relationships among the genes encoding MHC molecules and the specific antigen receptors relatively rare Ig superfamily (Igsf) domain type with each other, the Cl domain (Du Pasquier and Chrétien 1996). Cl domains are characterized by their strand/loop composition (Williams and Barclay 1988) and so far have not been found outside gnathostome vertebrates, the only ones that somatically
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Physical mapping of the class I regions of the rat major histocompatibility complexlarge part of the telomeric class I region, RT1-C/M. The RT1-A. region is shown to contain three class I genes and is located between the Sacm21 and Ringl genes. Sequence data indicate that the H2-K and RT1-A regions are localized at orthologous positions. For the RT1-C/M. region four contigs could
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發(fā)表于 2025-3-22 18:47:37 | 只看該作者
Polymorphic olfactory receptor genes and HLA loci constitute extended haplotypesd and sequenced in any organism, we have identified 27 OR genes between HLA-F and HFE, of which so far 23 are located within about 650 kilobasepairs between HLA-F and RFP. Their products could be involved in the recognition of individual-specific, MHC-dependent odours and be tailored to perform this
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發(fā)表于 2025-3-23 07:24:00 | 只看該作者
Transposable elements and the metamerismatic evolution of the HLA class I region and sequential interrelationships between members of the multicopy HLA class I and PERB11 (MIC) gene families, human endogenous retroviruses (HERVs) and retroelements that are distributed within this region. Analysis and mapping of genomic sequence from PERB 11.2 (MICB) to HLA-F has revealed that t
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