| 書目名稱 | Macromolecular Anticancer Therapeutics |
| 編輯 | L. Harivardhan Reddy,Patrick Couvreur |
| 視頻video | http://file.papertrans.cn/622/621043/621043.mp4 |
| 概述 | Macromolecular anticancer therapeutics encompasses macromolecule-conjugated anticancer prodrugs or macromolecules themselves for the treatment of cancer.Emphasizes various types and aspects of macromo |
| 叢書名稱 | Cancer Drug Discovery and Development |
| 圖書封面 |  |
| 描述 | .In spite of the development of various anticancer drugs, the therapy of cancer has remained challenging?for decades. The current therapy of cancer is overwhelmed because of the inability to deliver therapeutics to all regions of a tumor in effective therapeutic concentrations, intrinsic or acquired resistance to the treatment with currently available agents via genetic and epigenetic mechanisms, and toxicity. As a result, cancer therapy using conventional therapeutics and different types of treatment regimens using this therapeutics has not led to a convincing survival benefit of the patients. In this context, Macromolecular therapeutics offer several advantages over conventional low molecular therapeutics by various ways such as, enable the use of larger doses of these agents by limiting the toxicity, by enhanced permeability and retention into tumors, by tumor targeting using tumor-specific antibodies, by specific inhibition of oncogenes using anticancer oligonucleotides etc. Cancer treatment using this macromolecular therapeutics has considerably improved the survival benefit for patients. As a result, various macromolecular therapeutics are already commercialized or are under |
| 出版日期 | Book 2010 |
| 關(guān)鍵詞 | cancer; cancer therapy; cancer treatment; chemistry; classification; drug; hormones; imaging; immunotherapy; |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4419-0507-9 |
| isbn_softcover | 978-1-4614-2492-5 |
| isbn_ebook | 978-1-4419-0507-9Series ISSN 2196-9906 Series E-ISSN 2196-9914 |
| issn_series | 2196-9906 |
| copyright | Springer-Verlag New York 2010 |
|Archiver|手機版|小黑屋|
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