| 書(shū)目名稱 | Macrolide Antibiotics | | 編輯 | Wolfgang Sch?nfeld,Herbert A. Kirst | | 視頻video | http://file.papertrans.cn/622/621038/621038.mp4 | | 叢書(shū)名稱 | Milestones in Drug Therapy | | 圖書(shū)封面 |  | | 描述 | There are only very few chemical classes of antibiotics in medical use, and these have originated over a span of more than 60 years of research. Almost half a century ago, the first member of the macrolides, erythromycin, was introduced as a treatment option for bacterial infections. Erythromycin is a very complex fermentation product obtained from the soil bacterium Saccharopolyspora ery- thraea (originally named Streptomyces erythreus). The success of erythromycin, based on its efficacy and tolerability, stimulated researchers throughout the world to undertake intense efforts to understand the biology and chemistry of macrolides and to use this experience to improve the properties of this compound class. The second generation of macrolides, based on chemical modifications of erythromy- cin, is currently being in broad use, especially for treatment of respiratory tract infections. We presently foresee the introduction of a new generation of macro- lides, i. e. the ketolides, which have the potential to overcome rising resistance problems. This monograph is intended to give the interested reader an overview on "macrolide experience", covering important areas from basic research to | | 出版日期 | Book 2002 | | 關(guān)鍵詞 | Antibiotika; Infektionskrankheiten; Sexually Transmitted Diseases; antibiotics; asthma; bacteria; bacteria | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-0348-8105-0 | | isbn_softcover | 978-3-0348-9438-8 | | isbn_ebook | 978-3-0348-8105-0Series ISSN 2296-6056 Series E-ISSN 2296-6064 | | issn_series | 2296-6056 | | copyright | Springer Basel AG 2002 |
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