書目名稱 | Lymphocytes, Macrophages, and Cancer | 編輯 | Georges Mathé,Irène Florentin,Marie-Christine Simm | 視頻video | http://file.papertrans.cn/590/589212/589212.mp4 | 叢書名稱 | Recent Results in Cancer Research | 圖書封面 |  | 描述 | Fresh living Bacillus Calmette-Guerin (BeG), injected i.v. into (C57BI/ 6xDBA/2)FI mice, activated peritoneal macrophages rendering them highly cytotoxic for tumor cells in vitro. This cytotoxic activity w~s already maximal 14 days after injection of 1 mg of BCG and remained stable when 3 or 5 mg of BCG were given. At the same time spleen cells of the BCG-treat~d mice showed strongly depressed responses to the T-cell mitogens,PHA and Con A, irrespective of the dose of BCG injected. The inhibitory effect was shown to be mediated by suppressor cells which had characteristics of macrophages since they could be removed by carbonyl iron and magnet treatment and were adherent to plastic. In contrast to it was observed after injec- tion of 1 mg of BCG, these suppressor cells alone did not account for the depression of T-cell re.sponses induced by higher doses of BCG. Nylon-nonadherent cell populations obtained from spleen cells treated with 3 or 5 mg BCG partially retained the inhibitory activity suggesting that suppressor T cells were also induced after injection of high doses of BCG. In contrast, the responses to the B-cell mitogen LPS of unfractionated and macrophage-depleted spleen ce | 出版日期 | Book 1976 | 關鍵詞 | cancer; cell; lymphocytes; macrophages; neoplasm; tumor | 版次 | 1 | doi | https://doi.org/10.1007/978-3-642-81049-7 | isbn_softcover | 978-3-642-81051-0 | isbn_ebook | 978-3-642-81049-7Series ISSN 0080-0015 Series E-ISSN 2197-6767 | issn_series | 0080-0015 | copyright | Springer-Verlag Berlin · Heidelberg 1976 |
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書目名稱Lymphocytes, Macrophages, and Cancer影響因子(影響力) 
書目名稱Lymphocytes, Macrophages, and Cancer影響因子(影響力)學科排名 
書目名稱Lymphocytes, Macrophages, and Cancer網(wǎng)絡公開度 
書目名稱Lymphocytes, Macrophages, and Cancer網(wǎng)絡公開度學科排名 
書目名稱Lymphocytes, Macrophages, and Cancer被引頻次 
書目名稱Lymphocytes, Macrophages, and Cancer被引頻次學科排名 
書目名稱Lymphocytes, Macrophages, and Cancer年度引用 
書目名稱Lymphocytes, Macrophages, and Cancer年度引用學科排名 
書目名稱Lymphocytes, Macrophages, and Cancer讀者反饋 
書目名稱Lymphocytes, Macrophages, and Cancer讀者反饋學科排名 
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