Titlebook: Long Non Coding RNA Biology; M.R.S. Rao Book 2017 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nat

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FLORA

Long Noncoding RNA: Genome Organization and Mechanism of Action,lation. However, in the late 1990s and early 2000s, the advent of high-throughput sequencing technologies and computational tools to analyze these large sequencing datasets facilitated the discovery of thousands of small and long noncoding RNAs (lncRNAs) and their functional role in diverse biologic

斜

清洗

Long Noncoding RNAs in the Yeast ,,n, and disease relevance remain in the early stages of characterization. Although many thousands of lncRNA transcripts recently have been found to emanate from the expansive DNA between protein-coding genes in animals, there are also hundreds that have been found in simple eukaryotes. Furthermore, l

木質(zhì)

Long Noncoding RNAs in Plants,lar and biological processes. Most lncRNAs are found in the nucleus and associate with chromatin, but lncRNAs can function in both nuclear and cytoplasmic compartments. Emerging work has found that many lncRNAs regulate gene expression and can affect genome stability and nuclear domain organization

kidney

Long Noncoding RNAs in Mammalian Development and Diseases,discovered. These advances have highlighted an intriguing paradox whereby the relative amount of protein-coding sequences remain constant but nonprotein-coding sequences increase consistently in parallel to increasing evolutionary complexity. It is established that differences between species map to

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使堅(jiān)硬

commune

Understanding the Role of lncRNAs in Nervous System Development,ral role in this process. In this chapter, we will highlight the identification and characterization of lncRNAs in nervous system development. We discuss the potential role of lncRNAs in nervous system and brain evolution, along with efforts to create comprehensive catalogues that analyze spatial an

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