| 書目名稱 | Local Anesthetics | | 編輯 | Gary R. Strichartz (Associate Professor) | | 視頻video | http://file.papertrans.cn/588/587592/587592.mp4 | | 叢書名稱 | Handbook of Experimental Pharmacology | | 圖書封面 |  | | 描述 | Local anesthetics are among the most widely used drugs. Their development over the past century ranges from a documented influence on Freud‘s Interpretation of Dreams 1 to the synthesis of the ubiquitously popular lidocaine, as described in Chapter 1. For surgical procedures the use of regional, epidural and intrathecal local anesthesia has increased continuously during the past decade. Local anesthetics are also applied by physicians to ameliorate unpleasant sensations and reactions to other procedures, such as tracheal intubation. The presence or the threat of cardiac arrhythmias is often countered by chronic administration oflocal anesthetic-like agents, such as lidocaine or procainamide. Relief of acute pain, accompanying dental manipulations, for example, and of chronic pain are also accomplished with traditional local anesthetics. And over-the-counter formula- tions of topical local anesthetics provide practitioners of solar indiscretion welcome relief from their otherwise unaccommodating sunburn. In all these applications the final effect of the local anesthetic is an inhibition of electrical activity, accomplished as a reduction or total blockade of action potentials. The p | | 出版日期 | Book 1987 | | 關(guān)鍵詞 | anesthesia; intubation; pain | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-71110-7 | | isbn_softcover | 978-3-642-71112-1 | | isbn_ebook | 978-3-642-71110-7Series ISSN 0171-2004 Series E-ISSN 1865-0325 | | issn_series | 0171-2004 | | copyright | Springer-Verlag Berlin Heidelberg 1987 |
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