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Titlebook: Lipid-Soluble Antioxidants: Biochemistry and Clinical Applications; A. S. H. Ong,L. Packer Book 1992 Springer Basel AG 1992 biochemistry.b

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發(fā)表于 2025-3-21 19:51:43 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Lipid-Soluble Antioxidants: Biochemistry and Clinical Applications
編輯A. S. H. Ong,L. Packer
視頻videohttp://file.papertrans.cn/587/586871/586871.mp4
叢書名稱Molecular and Cell Biology Updates
圖書封面Titlebook: Lipid-Soluble Antioxidants: Biochemistry and Clinical Applications;  A. S. H. Ong,L. Packer Book 1992 Springer Basel AG 1992 biochemistry.b
描述Antioxidants inhibit the formation and spread of free radicals which can be damaging in biological systems. Free radicals form in biological systems through metabolism, but it is also realized that exogenous environmental sources, such as radiation, food, and drugs, contribute significantly to the generation of free radicals in biological systems. Being reactive species, free radicals are short-lived and do not travel far from cellular targets. Their concentration in biological systems is very low and is difficult to detect directly by electron spin resonance spectroscopy (ESR). Indirect methods of reactions of radicals with specific biomolecules are also sufficiently sensitive to detect quantitatively their presence. Thus the response of antioxidant defenses which react with radical species, can serve as an indirect measure that free radicals have been formed. Redox-based antioxidants change their oxidation state and antioxidants become free radicals themselves. Often, however, the antioxidants give rise to more persistent free radicals, sometimes owing to delocalization of the lone electron around ring structures (in vitamin E, ubiquinones, and certain carotenes). Persistent free
出版日期Book 1992
關(guān)鍵詞biochemistry; biomolecules; membrane; metabolism; spectroscopy
版次1
doihttps://doi.org/10.1007/978-3-0348-7432-8
isbn_softcover978-3-0348-7434-2
isbn_ebook978-3-0348-7432-8
copyrightSpringer Basel AG 1992
The information of publication is updating

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沙發(fā)
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板凳
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The Reactivity of Tocotrienols and Other Lipid-Soluble Antioxidants Towards Peroxyl Radicalsbtained when .-tocotrienol-enriched human LDL was exposed to peroxyl radicals. Under both conditions, .-tocotrienol reacted with peroxyl radicals as rapidly as .-tocopherol, though both forms of vitamin E were consumed after ubiquinol-10.
地板
發(fā)表于 2025-3-22 07:50:12 | 只看該作者
Synergistic Effect of Lipid Hydroperoxyl Radical Scavenging and Lipid Hydroperoxide Reduction in thepholipid hydroperoxyl radicals (PLOO.) produced during lipid peroxidation can start a chain reaction, getting the hydrogen atom from a polyunsaturated fatty acid, which eventually contains a new carbon centered radical (1).
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Anti-Tumor and Anti-Tumor Promoting Activity of ,- and ,-Caroteneroved to have higher potency than .-carotene to suppress tumor promotion in two-stage skin and lung carcinogenesis experiments. Thus, α-carotene seems to be a promising agent for cancer control..Further study to find other types of useful carotenoids in natural materials, especially in our daily foods, was also carried out.
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發(fā)表于 2025-3-22 20:41:07 | 只看該作者
systems through metabolism, but it is also realized that exogenous environmental sources, such as radiation, food, and drugs, contribute significantly to the generation of free radicals in biological systems. Being reactive species, free radicals are short-lived and do not travel far from cellular
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發(fā)表于 2025-3-23 00:33:03 | 只看該作者
New Horizons in Vitamin E Research — The Vitamin E Cycle, Biochemistry, and Clinical Applications reactions in tissue injury. An overview will be given of the evidence for the occurrence of free radicals and the importance of antioxidant interventions with particular reference to the lipophilic antioxidant vitamin E (tocopherols and tocotrienols).
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發(fā)表于 2025-3-23 05:21:25 | 只看該作者
Physical/Chemical Studies of Vitamin E in Membranescopy. The membrane retains normal lamellar bilayer arrangement. A model for .-tocopherol-lipid interaction has been constructed using computer aided graphics. Protection offered to intact cells (spermatozoa) by .-tocopherol against peroxidation caused by UV treatment has been studied using biochemical methods and spin labeling ESR technique.
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發(fā)表于 2025-3-23 08:41:38 | 只看該作者
Vitamin E in Protection of Oxidative Impairment in Endothelial and Platelet Functionsve. Platelet aggregation was also inhibited by the supplementation in the order α > β . γ. δ. There was a strong inverse correlation between platelet aggregability and serum α-tocopherol levels of rats each given the analogues. These results suggest that a-tocopherol plays an important role in prevention of atherogenesis.
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