Titlebook: Lipid Metabolism and Membrane Biogenesis; Günther Daum Book 20041st edition Springer-Verlag Berlin Heidelberg 2004 Eukaryotes.Organelles.P

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4 Defects in cholesterol biosynthesis,f certain cholesterol biosynthetic intermediates may be toxic has been considered but not convincingly demonstrated. Collectively, these defects in cholesterol biosynthesis emphasize the beneficial effects of cholesterol and of products derived from pathway intermediates.

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1610-2096 sed are mammalian, plant and yeast cells as the most prominent and currently best studied systems in lipid biochemistry, cell and molecular biology. .978-3-642-05857-8978-3-540-40999-1Series ISSN 1610-2096 Series E-ISSN 1610-6970

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6 Sterol biochemistry and regulation in the yeast ,,e regulatory mechanisms governing sterol synthesis, extension of our current knowledge in yeast sterol metabolism predicts to yield valuable insight applicable to basic and applied problems in more complex organisms.

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,12 Baker’s Yeast: a rising foundation for eukaryotic sphingolipid-mediated cell signaling,ponents of lipid rafts, and also allow correct protein anchoring to membrane as components of GPI anchors. Novel methods and strategies are beginning to allow the placement of sphingolipids within broader cellular contexts.