Titlebook: Linkage Disequilibrium and Association Mapping; Analysis and Applica Andrew R. Collins Book 2007 Humana Press 2007 Allele.DNA.SNP.gene.gene

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thermolysis. Instrumental methods showed that pentaerythritol at temperatures above 190 °C, against the background of crystalline structural rearrangement in the presence of active co-reagents such as melamine, decomposes into formic and acetic aldehydes used in its synthesis. Those, at the indicate

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BRUNT

The Genetic Basis of Complex Traits,red. Elated by the early successes from cloning disease genes for monogenic disorders, the architects of the projects reasoned that complex human diseases were tractable to positional cloning methods. However, a schism emerged in the field, with hot debates regarding two competing hypotheses being p

LUCY

Linkage Disequilibrium Maps and Disease-Association Mapping,on identifying functional polymorphisms that predispose to complex diseases. Population-based approaches are concerned with exploiting linkage disequilibrium (LD) between single-nucleotide polymorphism (SNPs) and disease-predisposing loci. The utility of SNPs in association mapping is now well estab

Tremor

Coalescent Methods for Fine-Scale Disease-Gene Mapping,d/or association studies. Population-based association fine-mapping methods utilize linkage disequilibrium of alleles at high-density marker single-nucleotide polymorphisms with the functional polymorphism, generated as the result of shared ancestry of individuals within the population. Here, we rev

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