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Titlebook: Leukemia Stem Cells in Hematologic Malignancies; Haojian Zhang,Shaoguang Li Book 2019 The Editor(s) (if applicable) and The Author(s), und

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發(fā)表于 2025-3-21 18:26:53 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Leukemia Stem Cells in Hematologic Malignancies
編輯Haojian Zhang,Shaoguang Li
視頻videohttp://file.papertrans.cn/586/585301/585301.mp4
概述Introduces readers to the biology of leukemia stem cells.Emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies.Covers the molecular signatures of leu
叢書名稱Advances in Experimental Medicine and Biology
圖書封面Titlebook: Leukemia Stem Cells in Hematologic Malignancies; Haojian Zhang,Shaoguang Li Book 2019 The Editor(s) (if applicable) and The Author(s), und
描述.This book introduces readers to the biology of leukemia stem cells (LSCs) and emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies. It addresses the role of leukemia stem cells in different leukemia diseases and molecular signatures, as well as the metabolic and epigenetic regulation of leukemia stem cell function. With regard to solid tumors, a significant number of blood cancers are believed to be derived from leukemia stem cells (LSCs), which are responsible for disease progression, relapse and drug resistance. Consequently, new therapeutic strategies need to be developed by focusing on the complete eradication of LSCs. Given its scope, the book offers a valuable asset for graduate students and scientists in the fields of cell biology and cancer research etc..
出版日期Book 2019
關(guān)鍵詞leukemia stem cells; blood cancer; targeted therapy; drug resistance; disease relapse
版次1
doihttps://doi.org/10.1007/978-981-13-7342-8
isbn_softcover978-981-13-7344-2
isbn_ebook978-981-13-7342-8Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor
The information of publication is updating

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發(fā)表于 2025-3-21 20:49:50 | 只看該作者
RNA ,,-Methyladenosine Modification in Normal and Malignant Hematopoiesis,matopoietic stem cells, tissue development, circadian rhythm, heat shock or DNA damage response, and sex determination. Thus, it is not surprising that dysregulation of the m.A machinery is also closely associated with pathogenesis and drug response of both solid tumors and hematologic malignancies.
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發(fā)表于 2025-3-22 02:10:24 | 只看該作者
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發(fā)表于 2025-3-22 04:42:02 | 只看該作者
DNA Damage Response in Quiescent Hematopoietic Stem Cells and Leukemia Stem Cells,, the DDR of LSCs were summarized based on the major outcomes triggered by different pathways in specific leukemia, upon which some aspects for future investigations were envisioned under our currently limited scope of knowledge.
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