Titlebook: Lentiviral Vectors and Gene Therapy; David Escors,Karine Breckpot,Holly Stephenson Book 2012 The Author(s) 2012 cancer.clinical trial.gene

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摘要記錄

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Development of Retroviral and Lentiviral Vectors, pathogen such as HIV into a successful therapeutic tool would not be possible without thorough scientific investigation into the development of .-retrovirus vectors. In this chapter, we briefly recapitulate the major scientific steps that have led to the development of .-retrovirus and lentivirus vectors.

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Clinical Grade Lentiviral Vectors,ults of several other trials were published. More recently, lentiviral vectors have been used for the correction of human .-thalassaemia and adrenoleukodystrophy. In this chapter, we discuss the production of clinical grade retro and lentivectors for their application in human therapy.

宣誓書

Book 2012 could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was demonstrated at the beginning of this century aft