Titlebook: Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors; Maximilian Oberleitner Book 2018 The Edit

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assical, severe salt-wasting form to a classical simple-virilizing (non-salt-wasting) form to a mild, nonclassical form. In all patients, CAH involves varying degrees of cortisol deficiency and androgen excess. Females with CAH invariably have hyperandrogenic symptoms. Classical CAH presents in the

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Methods and Instrumentation,line NRK (Normal Rat Kidney, strain 52E) were used. Both cell lines were obtained from the Leibniz Institute DSMZ—German Collection of Microorganisms and Cell Cultures (Braunschweig, Germany). They grow on cell culture substrates as monolayers of cobblestone-like morphology.

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Book 2018bel-free. The sensors described provide integrative information of the cells under study with an adaptable time resolution (ranging from milliseconds to days). This information about the dynamic cell response to chemical, physical or biological stimuli defines a new paradigm in fundamental biomedica

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Objectives,Biosensors based on whole cells as the biological recognition unit (CBBs) have gained an increasing interest in the past years by research institutes focusing on the development of new technologies that can serve as basis for the label-free and non-invasive screening of living cells.

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