Titlebook: Kenzan Method for Scaffold-Free Biofabrication; Koichi Nakayama Book 2021 Springer Nature Switzerland AG 2021 3D cell printing.Biofabricat

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Position of the , Method in the Space-Time of Tissue Engineering,s promise for further substantial development. However, it is less appreciated that Kenzan’s success derives from being one of the most truly “engineering” methods among the robotic biofabrication technologies. This is not due only to the exquisite sophistication and precision of the two instruments

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,Development of the Bio 3D Printer “Regenova?,” the Robotic System, described led to the development of an automated bio 3D printer known by the commercial name Regenova, a comprehensively capable system which can be utilized in both research and commercial industrial tissue engineering applications. The chapter provides a step-by-step descriptions of (1)?the resea

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,Development of a Compact Bio 3D Printer, “S-PIKE?”,In regenerative medicine, some cell products are used as cell injections, while others are used as a graft with three-dimensional (3D) structures. Using the Kenzan method, it is possible to produce large 3D cell structures that are several centimeters in size. Cyfuse Biomedical K.K. (Cyfuse) is deve

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Scaffold-Free Biofabrication of Liver, to that in the human body for investigations of liver disease and medical treatment has been challenging. Many studies have described in vitro human liver tissue models based on two-dimensional cultures of primary hepatocytes. However, those models lost their function rapidly. Efforts to engineer a

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Cardiac Tissue Creation with the Kenzan Method,ased on the use, or lack thereof, of supporting biomaterials: also known as “scaffolds.” The scaffold-free method uses spheroids as building blocks and depends on the spheroids to produce their own extracellular matrix, which in turn directs the spheroids’ growth and development. This method creates

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Scaffold-Free Autologous Cell-Based Vascular Graft for Clinical Application,ally for small-caliber blood conduits. We have researched and developed a scaffold-free small-caliber vascular graft using a “Kenzan method Bio-3D Printer” to assemble multicellular spheroids to construct a three-dimensional structure predesigned on a computer system. This technique has enabled the