Titlebook: Islets of Langerhans; Md. Shahidul Islam Living reference work 20200th edition

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BILL

Pelvic-Floor

Anionic Transporters and Channels in Pancreatic Islet Cells,ulin release, the present chapter, which deals with anionic transporters and channels in pancreatic islet cells, concerns mainly a second modality for the control of insulin secretion by the hexose. In such a perspective, it draws attention to the NBCe1 Na./HCO.. cotransporters, the volume-regulated

Heretical

,Apoptosis in Pancreatic β-Islet Cells in Type 1 and Type 2 Diabetes,utoimmune insulitis causes an absolute insulin deficiency triggered by an extrinsic receptor-mediated pathway, which activates a cascade of caspase family reaction. The etiology of type 2 diabetes is multifactorial, including obesity-associated insulin resistance, defective insulin secretion, and lo

啤酒

Approaches for Imaging Pancreatic Islets: Recent Advances and Future Prospects,ther in vitro studies or quite indirect in vivo measurements. Methods to noninvasively and repeatedly evaluate the mass and function of β-cells in vivo, two parameters that are central to the study of diabetes, are expected to change our understanding of this disease. However, and in spite of remark

SNEER

ATP-Sensitive Potassium Channels in Health and Disease, β-cell is finely balanced; increased activity prevents insulin secretion, whereas reduced activity stimulates insulin release. B-cell metabolism tightly regulates K. channel gating, and if this coupling is perturbed, two distinct disease states can result. Diabetes occurs when the K. channel fails

Saline

SPALL

Beta Cell Store-Operated Ion Channels,lation trigger Ca.-dependent signaling pathways that regulate insulin exocytosis. Much is known about ATP-sensitive K. and voltage-gated Ca. currents that contribute to Ca.-dependent signal transduction in β-cells and insulin secretion, but relatively little is known about other Ca. channels that re

pulse-pressure

Calcium Signaling in the Islets,that have clarified details of Ca. signaling in the rodent islets. Our understanding of the mechanisms and the roles of Ca. signaling in the human islets, under physiological conditions, has been influenced by extrapolation of the rodent data obtained under suboptimal experimental conditions. More r

BRAND

Chloride Channels and Transporters in Beta-Cell Physiology,e of additional ionic cascades of events within the stimulus-secretion coupling. The purpose of this review is to introduce the reader to the role of the long-relegated and largely ignored subject of intracellular Cl. concentration ([Cl.].). The regulation of [Cl.]. by transporters and channels, and