Titlebook: Ionic Actions on Vascular Smooth Muscle; with Special Regard Eberhard Betz Book 1976 Springer-Verlag Berlin Heidelberg 1976 adenosine.brai

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Calcium in the Vascular Smooth Muscle Cell,t can be accounted for by diffusion delays, or so slowly as to indicate that depolarization can utilize cell Ca stores in the absence of extracellular Ca. Electrical activity plays an important role in this vessel’s activity. The artery usually fires one or two action potentials when depolarized (8)

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Spontaneous Actions of Small Pial Vessels and the Response to Transmural Electrical Stimulation,er 80–250 μm). The animals were anaesthetized (Pentobarbital 25 mg/kg body weight) with spontaneous respiration. The acid-base status was determined from arterial blood and kept in a physiologic range by assisted respiration as needed. Mean arterial blood pressure remained constant during the experi

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Ionic Interaction in Pial Vascular Smooth Muscles,single vascular section. The pipette could be connected to different containers filled with artificial CSF. This allowed us to change the perivascular ionic milieu rapidly. If the perivascular pH is changed, one can see by switching the micropipette from one container with CSF of pH 7.6 to another o

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Measurements of Pial Perivascular Ion Activities by Means of Ion Sensitive Microelectrodes,ral authors (1, 6). Their results have modified the hypothesis that H.-ions are the main factor controlling cerebral vascular smooth muscle tone (7). These experiments have demonstrated that other ions as well, mainly Ca., K., Mg. and Cl., are involved in this regulatory mechanism. In this concept t

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The Action of K+ at the Cerebral Vessels,rs. More recently it has become apparent that changes in local pH do not invariably correlate with changes in CBF (1). Other vasoactive mechanisms must be involved and a possible role for the K. ion has been suggested. K. is known to be vasoactive in other vascular beds (6), and although the mean K.

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https://doi.org/10.1007/978-3-642-66427-4adenosine; brain; calcium; cell; muscle; therapy

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Vascular Effects of Potassium in Physiologic Concentration Range,n the range between zero and 15 mM (8, 12, 13). A decrease in K. increases the tone of vascular smooth muscle, and an increase has a dilating effect. The maximum effectiveness of changes in the K. concentration has been observed in the isolated artery in the range between 2 and 6 mM (12, 13).