Titlebook: Ion Channel Reconstitution; Christopher Miller Book 1986 Springer Science+Business Media New York 1986 brain.Calcium.Lipid.muscle.pharmaco

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Skeletal Muscle Sodium Channelshe sarcolemma and T-tubular membranes. The time- and voltage-dependent characteristics of the currents regulated by this channel have been studied extensively over the past few decades, first using the traditional approach of voltage clamp (Adrian ., 1970) and more recently at the single-channel lev

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Reconstitution of the Sodium Channel from , 2; Cahalan, 1980) is perhaps the archetypical voltage-gated channel. Advances in the biochemical isolation, characterization, and functional reconstitution of Na.? channel proteins from the electroplax of electric fish (Miller ., 1983; Norman ., 1983; Rosenberg ., 1984a, b), mammalian skeletal muscl

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The Reconstituted Sodium Channel from Brainole in impulse conduction, it has been the subject of extensive investigations by electrophysiological and biochemical techniques to understand its structure and function. Sodium channels have been solubilized in detergents and purified from eel electroplax (Agnew ., 1978; Miller ., 1983), rat muscl

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Gating of Batrachotoxin-Activated Sodium Channels in Lipid Bilayersstem for the study of various aspects of channel behavior. Use of the steroidal alkaloid toxin batrachotoxin (BTX) was a crucial aid in making the first electrical recordings from voltage-dependent sodium channels incorporated into artificial lipid membranes from native membrane vesicles from rat br

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Ion Conduction Through Sodium Channels in Planar Lipid Bilayersnt Na. channel being no exception. Apart from their use in identifying ion channels, measurements of ion selectivities and single-channel conductances also provide insight into the biophysical mechanisms underlying ion permeation through the channels. Such measurements and their interpretations may

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