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Titlebook: Intracellular Signal Transduction: The JAK-STAT Pathway; Andrew F. Wilks,Ailsa G. Harpur Book 1996 Springer-Verlag Berlin Heidelberg 1996

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書目名稱Intracellular Signal Transduction: The JAK-STAT Pathway
編輯Andrew F. Wilks,Ailsa G. Harpur
視頻videohttp://file.papertrans.cn/474/473132/473132.mp4
叢書名稱Molecular Biology Intelligence Unit
圖書封面Titlebook: Intracellular Signal Transduction: The JAK-STAT Pathway;  Andrew F. Wilks,Ailsa G. Harpur Book 1996 Springer-Verlag Berlin Heidelberg 1996
描述This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself. An interesting addition to the book is the chapter on the use of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling.
出版日期Book 1996
關(guān)鍵詞Drosophila; cytokine; protein; receptor; signal transduction; transcription
版次1
doihttps://doi.org/10.1007/978-3-662-22050-4
isbn_softcover978-3-662-22052-8
isbn_ebook978-3-662-22050-4Series ISSN 1431-0414
issn_series 1431-0414
copyrightSpringer-Verlag Berlin Heidelberg 1996
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978-3-662-22052-8Springer-Verlag Berlin Heidelberg 1996
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Intracellular Signal Transduction: The JAK-STAT Pathway978-3-662-22050-4Series ISSN 1431-0414
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發(fā)表于 2025-3-22 12:33:56 | 只看該作者
1431-0414 of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling.978-3-662-22052-8978-3-662-22050-4Series ISSN 1431-0414
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Somatic Cell Genetic Dissection of Interferon Signal Transduction Pathways,as proved to be a general feature of all signaling downstream of cytokine receptors, and provided the mechanistic underpinning for the JAK-STAT pathway. The first piece in the puzzle was the generation of cell lines defective in IFNα/β signaling.
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