Titlebook: International Conference on Innovative Computing and Communications; Proceedings of ICICC Ashish Khanna,Deepak Gupta,Aboul Ella Hassanien C

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-malarial and anti-cryptosporidium strategies. Therefore, the development of targeted isoform selective inhibitors for these enzymes are of paramount importance. The first generation of PI3K inhibitors have recently been clinically approved for a number of different cancers, highlighting their thera

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Pradeep Kumar Singh,Showmik Setta,Pijush Kanti Dutta Pramanik,Prasenjit Choudhuryfully designed to spare gastrointestinal toxicity, but predisposed patients to increased cardiovascular risks. These health complications from NSAIDs prompted interest in the downstream effectors of the COX enzymes as novel drug targets. This chapter describes various safety issues with tNSAIDs and

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Kumud Tiwari,Sachin Kumar,R. K. Tiwarirchers at Rh?ne Poulenc, who named it rubidomycin. Later on, it became clear that rubidomycin and daunomycin were identical and daunorubicin became the only name for this compound. In 1969, Arcamone and his co-workers succeeded in isolating and purifying doxorubicin (14-hydroxydaunomycin) from . var

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Muhammad Ali,Waqas Arshadnd related non-steroidal antiinflammatory drug (NSAID:s). is well established, and apparently correlates with the capacity to inhibit the formation of cyclooxygenase products, notably PGE., PGD2, and PGI2. Although these three substances are considered proinflammatory and potently enhance the respon

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