| 書目名稱 | Inotropic Stimulation and Myocardial Energetics | | 編輯 | Hj. Just,Ch. Holubarsch,H. Scholz | | 視頻video | http://file.papertrans.cn/468/467644/467644.mp4 | | 圖書封面 |  | | 描述 | Inotropic stimulation of the myocardium, as well as vasodilation and diuresis as essential principles in the treatment of congestive heart failure have recently met with considerable criticism and reevaluation. It is generally agreed that unloading of the heart, either through vasodilation and/or diuresis, improves the working conditions of the dilated, failing heart. It reduces myocar- dial oxygen consumption through reduction of chamber radius and, thereby, wall tension as the major determinants of myocardial oxygen consumption. Inotropic stimulation, quite in contrast, does not conserve oxygen. It rather consumes energy and that may be disadvantageous in situations of compromised oxygen supply and energy metabolism of the working myocardium. However, under conditions of suf- ficient oxygen supply and metabolic support inotropic stimulation may bring about in- creased pumping and subsequent improvement of myocardial failure. In recent years it could convincingly be demonstrated that vasodilation leads to symp- tomatic improvement of congestive heart failure, improvement of exercise tolerance, and it prolongs life - especially in the case of ACE-inhibitors and the combination of h | | 出版日期 | Conference proceedings 1989 | | 關(guān)鍵詞 | Hydra; arrhythmia; heart; heart failure; metabolism | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-662-07908-9 | | isbn_softcover | 978-3-662-07910-2 | | isbn_ebook | 978-3-662-07908-9 | | copyright | Springer-Verlag Berlin Heidelberg 1989 |
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