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Titlebook: Inflammatory Diseases and Copper; The Metabolic and Th John R. J. Sorenson Book 1982 The Humana Press Inc. 1982 Amino acid.Arthritis.Lipid.

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發(fā)表于 2025-3-21 16:40:50 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Inflammatory Diseases and Copper
副標(biāo)題The Metabolic and Th
編輯John R. J. Sorenson
視頻videohttp://file.papertrans.cn/465/464720/464720.mp4
叢書名稱Experimental Biology and Medicine
圖書封面Titlebook: Inflammatory Diseases and Copper; The Metabolic and Th John R. J. Sorenson Book 1982 The Humana Press Inc. 1982 Amino acid.Arthritis.Lipid.
描述In 1928, it was discovered that copper was essential for normal human metabolism. A decade later, in 1938, it was observed that patients with rheu- matoid arthritis exhibited a higher than normal serum copper concentration that returned to normal with remission of this disease. Thirteen years later, it was found that copper complexes were effective in treating arthritic dis- eases. The first report that copper complexes had antiinflammatory activity in an animal model of inflammation appeared twenty-two years after the dis- covery of essentiality. In 1976, it was suggested that the active forms of the antiarthritic drugs are their copper complexes formed in vivo. This sugges- tion has been confirmed and extended in the interim in over 200 recent publications. Individual biomedical scientists from many countries who have published in these areas recently saw a need for a meeting to exchange current re- supporting new hypotheses. We search results and discuss the evidence met on the University of Arkansas Medical Sciences campus in Little Rock, Arkansas, August 10-13, 1981. Participants came from Australia, England, France, Germany, Israel, Italy, The Netherlands, Norway, Poland, Sco
出版日期Book 1982
關(guān)鍵詞Amino acid; Arthritis; Lipid; Oxidation; inflammation; metabolism; protein; rheumatic diseases; rheumatoid a
版次1
doihttps://doi.org/10.1007/978-1-4612-5829-2
isbn_softcover978-1-4612-5831-5
isbn_ebook978-1-4612-5829-2
copyrightThe Humana Press Inc. 1982
The information of publication is updating

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發(fā)表于 2025-3-21 21:30:23 | 只看該作者
Ceruloplasmin: Experimental Anti-Inflammatory Activity and Physicochemical Propertiesn Germany (reviewed by Sorenson and Hangarter, 1977). Both treatments were given by the intravenous route, not in favor among clinicians. The discovery of cortisone at the same period and progress in the chemistry of non-steroidal AI compounds put for a while the copper molecules into disuse.
板凳
發(fā)表于 2025-3-22 03:45:42 | 只看該作者
Wilson’s Disease changes. The liver is not only the organ which is most frequently and severely affected by the ., but it . also the . of the etiologic biochemical abnormality which causes the retention of the excessive oncentrations of copper (1).
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Copper Homeostasiswith mechanisms to conserve copper when the dietary level is low and rid the body of excess when necessary. The following discussion describes our current knowledge of the mechanisms involved in the regulation of copper homeostasis.
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Cu-Zn Superoxide Dismutasefferent prosthetic metals, Cu, Zn-, Fe-, and Mn-enzyme (2-5). This enzyme catalyzes the reaction . (6). There is considerable evidence that this enzyme is absolutely necessary for the survival of all oxygen-metabolizing cells (1).
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