Titlebook: Inflammation and Epilepsy: New Vistas; Damir Janigro,Astrid Nehlig,Nicola Marchi Book 2021 Springer Nature Switzerland AG 2021 Brain-body

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Progress in Inflammation Researchhttp://image.papertrans.cn/i/image/464680.jpg

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https://doi.org/10.1007/978-3-030-67403-8Brain-body Axis; Cerebrovasculature; Epilepsy; Inflammatory Mechanisms; Microbiota; Maternal and Perinata

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978-3-030-67405-2Springer Nature Switzerland AG 2021

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Inflammation and Epilepsy: New Vistas978-3-030-67403-8Series ISSN 1422-7746 Series E-ISSN 2296-4525

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Pro- and Anti-inflammatory Neurovascular Processes in Epilepsy: A Fragile and Dynamic Equilibrium,ephalitis. In the last two decades, preclinical and clinical studies provided growing evidence to support a link between brain or peripheral inflammation, seizures, and epileptogenesis. Inflammation is activated to restore tissue homeostasis and to initiate repair programs by the activation of pro-r

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Emerging Molecular Mechanisms of Neuroinflammation in Seizure Disorders,ed brain but contributes to neuronal hyperexcitability underlying seizure generation, cell loss, and neurological comorbidities. Several molecules that constitute the inflammatory . in the epileptogenic area activate intracellular signaling pathways in neurons, glia, and cellular components of the b

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Glial Mechanisms of Inflammation During Seizures,. The expression of these reactive phenotypes leads to the dysregulation of physiological functions normally fulfilled by these glial cells and to the acquisition of inflammatory properties that influence the activity and the fate of brain cells, including neurons, glia, and cells of the blood vesse

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Perivascular Inflammation and Extracellular Matrix Alterations in Blood-Brain Barrier Dysfunction a is observed in several neurological diseases, including epilepsy. Prolonged BBB dysfunction and subsequent perivascular inflammation as well as alterations in the extracellular matrix (ECM) play an important role in epileptogenesis. In this chapter we aim to give an overview of the processes involv

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