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Titlebook: Induced Mutagenesis; Molecular Mechanisms Christopher W. Lawrence (Chairman) Book 1983 Plenum Press, New York 1983 Hamster.Mamma.attention.

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書目名稱Induced Mutagenesis
副標題Molecular Mechanisms
編輯Christopher W. Lawrence (Chairman)
視頻videohttp://file.papertrans.cn/464/463849/463849.mp4
叢書名稱Basic Life Sciences
圖書封面Titlebook: Induced Mutagenesis; Molecular Mechanisms Christopher W. Lawrence (Chairman) Book 1983 Plenum Press, New York 1983 Hamster.Mamma.attention.
描述Concern is often expressed that our environment may include an increasingly large variety of mutagens, but the extent of the potential hazard they pose has yet to be fully evaluated. A variety of empirical procedures has been devised with which to estimate the mutagenic potency of suspect agents, and the relative merits of different tests are currently under debate. Although such tests are of great value, and are indeed indispensable, they are not, nevertheless, sufficient. In the long term, accurate estimation of hazard will also require a better understanding of the various mechanisms of mutagenesis, and in many instances these remain remarkably elusive. Our knowledge and appreciation of the problem has increased substantially over the last few years, but the precise way in which many mutagens cause mutations is not yet known. The aims of this conference were therefore two-fold. The first was to survey present information about mutagenic mechanisms, drawing together data from work with various experimental approaches and organisms, in order to discern the principles governing the action of different mutagens. The second was to examine the implications of such principles for the e
出版日期Book 1983
關鍵詞Hamster; Mamma; attention; biology; energy; evaluation; microbiology; mutagen; mutagenesis; mutation; research
版次1
doihttps://doi.org/10.1007/978-1-4684-4382-0
isbn_softcover978-1-4684-4384-4
isbn_ebook978-1-4684-4382-0
copyrightPlenum Press, New York 1983
The information of publication is updating

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Differential Sensitivity to Certain DNA-Damaging Treatments, Including 8-Methoxypsoralen Plus 340 nm a simple bacterial model where the simplest interpretation of the data suggests that the structure rather than sequence of the DNA seems to affect the probability of interaction with intercalating agents such as 8-methoxypsoralen (8-MOP).
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The Induction of Resistance to Alkylation Damage in Mammalian Cellsls. We now have good biological evidence for the existence of an adaptive DNA repair pathway in cultured rodent and human cell lines (2). In order to set the scene for our recent findings in mammalian cells, we should first consider what is presently known about .. . adaptation.
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Book 1983e has yet to be fully evaluated. A variety of empirical procedures has been devised with which to estimate the mutagenic potency of suspect agents, and the relative merits of different tests are currently under debate. Although such tests are of great value, and are indeed indispensable, they are no
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