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Titlebook: Increasing the Therapeutic Ratio of Radiotherapy; Philip J. Tofilon,Kevin Camphausen Book 2017 Springer International Publishing Switzerla

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書目名稱Increasing the Therapeutic Ratio of Radiotherapy
編輯Philip J. Tofilon,Kevin Camphausen
視頻videohttp://file.papertrans.cn/464/463352/463352.mp4
概述Focuses on potential targets/strategies for increasing the therapeutic ratio for radiotherapy.Discusses radiotherapies with an integrated approach.Highlights advances in approaches as well as the barr
叢書名稱Cancer Drug Discovery and Development
圖書封面Titlebook: Increasing the Therapeutic Ratio of Radiotherapy;  Philip J. Tofilon,Kevin Camphausen Book 2017 Springer International Publishing Switzerla
描述Current cancer therapies are focused on three general strategies: modifying intrinsic radiosensitivity via molecular targeting, manipulating microenvironmental factors to enhance tumor susceptibility to radiation, and improving delivery of radiation to critical tumor locations while sparing normal tissues. The goal of this volume is to describe a number of promising approaches corresponding to each strategy..In general, research in radiation oncology tends to be siloed into fundamental biology, physics or treatment delivery. The strategies for improving therapeutic ratio encompassed in this book will involve each of these components of radiation oncology. Thus, they will illustrate the variety of disparate approaches available for potentially improving the efficacy of radiotherapy, which may then stimulate discussion across disciplines and foster further translational investigations..Although a goal of each chapter will be to highlight advances within an approach, of equal importance will be the delineation of barriers to successful clinical application and how to overcome or minimize such impediments. Along these lines, because therapeutic ratio incorporates both tumor and normal
出版日期Book 2017
關(guān)鍵詞DNA; DNA repair; Radiotherapy; Therapeutic Ratio; Tumors; Radiaton Oncology; antibacterial drug resistance
版次1
doihttps://doi.org/10.1007/978-3-319-40854-5
isbn_softcover978-3-319-82201-3
isbn_ebook978-3-319-40854-5Series ISSN 2196-9906 Series E-ISSN 2196-9914
issn_series 2196-9906
copyrightSpringer International Publishing Switzerland 2017
The information of publication is updating

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Receptor Tyrosine Kinases as Targets for Enhancing Tumor Radiosensitivity, have been successes with molecularly targeted agents as monotherapies, most solid tumors display only a transient and modest response to single-targeted agents. As such, there has been significant effort in combining molecularly targeted agents with radiotherapy. Receptor tyrosine kinases (RTKs) pl
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