| 書(shū)目名稱 | In Vitro Neurotoxicology | | 副標(biāo)題 | Methods and Protocol | | 編輯 | Lucio G. Costa,Gennaro Giordano,Marina Guizzetti | | 視頻video | http://file.papertrans.cn/464/463033/463033.mp4 | | 概述 | Serves a wide audience seeking to assess or characterize potential neurotoxicity.Includes detailed, lab-ready protocols for numerous model system, both mammalian and non-mammalian.Features key tips an | | 叢書(shū)名稱 | Methods in Molecular Biology | | 圖書(shū)封面 |  | | 描述 | .In recent years, the need to develop acceptable alternatives to conventional animal testing for neurotoxicity and developmental neurotoxicity has been increasingly recognized, and much effort is being directed toward the development of alternative models, utilizing mostly mammalian cells in culture but also non-mammalian model systems.? .In Vitro Neurotoxicology: Methods and Protocols. presents a series of cellular, biochemical, and molecular methodological protocols in the area of in vitro neurotoxicology, with an emphasis on mammalian cell culture systems.? Opening with a section on methodologies for preparing several cellular systems of variable complexity, amenable for in vitro neurotoxicological studies, the thorough volume continues with coverage of methods to measure cellular death and major mechanisms, methods for assessing mechanisms of nervous system cell toxicity related to impairment of cell signaling, while a final section illustrates additional methods for assessing important nervous system processes such as cell proliferation, neuritogenesis, and synaptogenesis.? Written in the highly successful .Methods in Molecular Biology?. series format, chapters include introdu | | 出版日期 | Book 2011 | | 關(guān)鍵詞 | Cell signaling impairment; Cellular death; Chemicals; Drugs; Environmental contaminants; Mammalian cell c | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-61779-170-3 | | isbn_softcover | 978-1-4939-5858-0 | | isbn_ebook | 978-1-61779-170-3Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media, LLC 2011 |
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