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Titlebook: Immunotherapy for Pediatric Malignancies; Juliet C. Gray,Aurélien Marabelle Book 2018 Springer International Publishing Switzerland 2018 A

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發(fā)表于 2025-3-21 19:51:50 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Immunotherapy for Pediatric Malignancies
編輯Juliet C. Gray,Aurélien Marabelle
視頻videohttp://file.papertrans.cn/463/462304/462304.mp4
概述Comprehensively reviews immunotherapy strategies currently used in the treatment of cancer and how these are applicable to pediatric malignancies.Addresses key issues, such as immune-related toxicitie
圖書封面Titlebook: Immunotherapy for Pediatric Malignancies;  Juliet C. Gray,Aurélien Marabelle Book 2018 Springer International Publishing Switzerland 2018 A
描述.This book provides a comprehensive overview of current immunotherapy strategies, and how these may be applicable to childhood cancers. The first part of the book reviews how the immune system recognizes cancer, and the various escape mechanisms allowing tumour growth. The importance of the tumor microenvironment and the challenges this may present to achieving effective immunotherapy are discussed. Monoclonal antibodies, cellular, cytokine and vaccine therapies are all comprehensively reviewed, with particular focus on their potential application to pediatric cancers. Practical aspects of delivering such therapies to children, likely toxicities and potential biomarkers are considered. Finally, consideration is given to how, in the longer term, such therapies may be combined with conventional therapies such as chemotherapy and radiotherapy..Edited by two distinguished pediatric oncologists with a collection of chapters from the most authoritative experts in cancer immunotherapy, this is an indispensable volume for pediatric oncologists and physicians working in childhood cancer care.. .
出版日期Book 2018
關(guān)鍵詞Allogeneic Stem Cell Transplantation; Monoclonal Antibody; T-cell therapy; cancer; cytokine; immunotherap
版次1
doihttps://doi.org/10.1007/978-3-319-43486-5
isbn_softcover978-3-319-82837-4
isbn_ebook978-3-319-43486-5
copyrightSpringer International Publishing Switzerland 2018
The information of publication is updating

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Overcoming Immune Suppression in the Tumor Microenvironment: Implications for Multi-modal Therapy,h of which release a wave of tumor antigens. The choice of whether to treat these antigens as tolerizing or immunizing is fundamental to generating an effective immune response against the tumor. In this chapter we consider immunosuppressive mechanisms in the tumor microenvironment from the perspect
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Juliet C. Gray M.A., FRCPCH, Ph.D.,Paul M. Sondel M.D., Ph.D.ion with disease duration. Patients with cerebellar degeneration showed lower resting MSNA than the healthy controls, while there were no significant differences of age, resting HR, or resting BP between the patients and healthy controls. In patients with cervical spondylosis, the resting MSNA was p
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