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Titlebook: Immunoconjugate Therapy of Hematologic Malignancies; Steven T. Rosen,Timothy M. Kuzel Book 1993 Springer Science+Business Media New York 1

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發(fā)表于 2025-3-25 07:04:04 | 只看該作者
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Treatment of leukemia with radiolabeled monoclonal antibodies,ting of clonogenic cells is abandoned, the effectiveness of nonspecific cell eradication remains inadequate. Improvements are clearly needed both in terms of targeting clonogenic cells and in the potency (relative to a given rate of normal tissue morbidity) of the cytotoxic agent. Radioimmunotherapy
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Use of bispecific antibodies in the therapy of tumors,sslinked, leading to the directed release of cytotoxic molecules from the effector cell. Many potentially useful MoAb are not of the appropriate isotype, and therefore are unable to activate human complement and/or trigger FcyR on human cells.
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lexes (conditioned stimulus-conditioned response; unconditioned stimulus-unconditioned response). The conditioned or acquired reflexes were optimistically offered as factual alternatives to “the fantastic speculations as to the existence of any possible subjective state in the animal which may be co
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George Sgouros,David A. Scheinbergeen scratched. The primary focus of this pioneering effort extends the competing response analysis across all experimental schedules, both classical and instrumental, as well as the interactions between the two. Appropriately, the analysis empha- sizes overt behavioral interactions, beginning with the simples978-1-4612-6312-8978-1-4612-6310-4
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