Titlebook: IgG4-Related Kidney Disease; Takao Saito,John H. Stone,Mitsuhiro Kawano Book 2016 Springer Japan 2016 IgG4.IgG4-related disease.IgG4RKD.Me

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Mitsuhiro Kawano,Kazunori Yamadais outstanding thesis contributes significantly to both topics within the field of Flavour Physics and sheds new light on the observed anomalies..978-3-030-19199-3978-3-030-19197-9Series ISSN 2190-5053 Series E-ISSN 2190-5061

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IgG4-Related Disease: History and Overviewng plasma cells; and, (6) favorable response to glucocorticoid therapy in most cases..The establishment of this entity originated with the discovery of high serum IgG4 concentration and marked IgG4-bearing plasma cell infiltration in patients with autoimmune pancreatitis (AIP). This was followed by

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Overview of IgG4-Related Kidney Diseaseerences in Japan. The most common histological feature of IgG4-RKD is tubulointerstitial nephritis, where the combination of IgG4-positive plasma cells and fiber bundles forms a characteristic fibrosis called “storiform” or “bird’s eye”. Glomerular lesions, most of which are membranous nephropathy,

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IgG4-Related Kidney Disease: Clinical and Laboratory Featuressinophilia, mild elevation in C-reactive protein concentration, and the presence of antinuclear antibody can be detected in addition to elevation of IgG and IgG4 concentrations. These serological abnormalities do not occur in all cases. In fact, recently reported cases expressed normal IgG4 concentr

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Retroperitoneal Fibrosis/Periaortitis and Hydronephrosise uncontrollable with corticosteroid alone and need an additional steroid-sparing immunosuppressive agent or urological intervention. Early detection of such conditions and the prompt initiation of appropriate treatment are necessary to improve the renal prognosis. Further studies are required to es

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Other Urogenital Lesions (Testis, Paratesticular Lesion, Bladder, Prostate etc.)ver, patients with IgG4-RD affecting these organs can also be asymptomatic. IgG4-RD of the testes, which often presents as a painless mass, has frequently been observed in younger patients, posing a challenge in diagnosis.