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Titlebook: Identification of Transcribed Sequences; Ute Hochgeschwender,Katheleen Gardiner Book 1994 Springer Science+Business Media New York 1994 Ch

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書目名稱Identification of Transcribed Sequences
編輯Ute Hochgeschwender,Katheleen Gardiner
視頻videohttp://file.papertrans.cn/461/460844/460844.mp4
圖書封面Titlebook: Identification of Transcribed Sequences;  Ute Hochgeschwender,Katheleen Gardiner Book 1994 Springer Science+Business Media New York 1994 Ch
描述The Human Genome Project, an endeavor to map and sequence the entire human genome, has been in existence for almost seven years. One result of this effort has been the development of increasingly detailed genetic and physical maps spanning large regions of virtually every chromosome. Paralleling this has been the increasingly high resolution mapping of many &wnetic diseases. Together, these developments have facilitated the isolation of specific disease genes and are now motivating the construction of comprehensive transcriptional maps. This latter endeavor represents a new facet of the genome project, and as such requires the recognition and solution of a new set of problems, with the attendant development and application of a new set of techniques. The First International Workshop on the Identification of Transcribed Sequences in the Human Genome was held in 1991 and was attended by 23 investigators. Discussions at this meeting were largely devoted to defining the magnitude of the problem and describing the available techniques. A small number of laboratories reported the development of new techniques (at that time, for example, exon trapping, cDNA hybrid selection, direct cDNA s
出版日期Book 1994
關(guān)鍵詞Chromosom; DNA; YAC; cloning; genes; hybridization; transcription
版次1
doihttps://doi.org/10.1007/978-1-4615-2562-2
isbn_softcover978-1-4613-6094-0
isbn_ebook978-1-4615-2562-2
copyrightSpringer Science+Business Media New York 1994
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978-1-4613-6094-0Springer Science+Business Media New York 1994
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d most important cultivated crop, equally consumed in different forms. In recent years, enormous progress in genomic advancement in fungal disease resistance has partially solved the problem throughout the globe. The landraces, conventional varieties, and wild species (primary, secondary, and tertia
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Introduction: Seven Blind Men and an Elephantgenes in man would be necessary. While the question of gene number has interested geneticists at least since Muller (1), it has also influenced thought on evolution and development. Indeed, the C-value paradox was important because of the implication that “simpler” organisms had more genetic complex
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Introduction: Seven Blind Men and an Elephantity than mammals. Now the number of human genes has become a question of practical relevance, affecting how we pursue comprehensive transcriptional mapping. I present here a short, critical review of papers representing the major approaches which have been used to address this question.
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