Titlebook: Hydroxamic Acids; A Unique Family of C Satya P. Gupta Book 2013 Springer-Verlag Berlin Heidelberg 2013 Anti-Cancer Agents.Antibacterial Age

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書目名稱Hydroxamic Acids影響因子(影響力)




書目名稱Hydroxamic Acids影響因子(影響力)學科排名




書目名稱Hydroxamic Acids網(wǎng)絡公開度




書目名稱Hydroxamic Acids網(wǎng)絡公開度學科排名




書目名稱Hydroxamic Acids被引頻次




書目名稱Hydroxamic Acids被引頻次學科排名




書目名稱Hydroxamic Acids年度引用




書目名稱Hydroxamic Acids年度引用學科排名




書目名稱Hydroxamic Acids讀者反饋




書目名稱Hydroxamic Acids讀者反饋學科排名

BROTH

WAG

Hydroxamates as Carbonic Anhydrase Inhibitors,tant physiological functions such as pH regulation, signaling, biosynthetic reactions, electrolyte secretion, etc. Unsubstituted sulfonamides act as high affinity inhibitors for the first type of these enzymes, whereas hydroxamates were also shown to strongly inhibit many of them. The investigated h

LEER

,Structure–Activity Relationship Studies of Hydroxamic Acids as Matrix Metalloproteinase Inhibitors,(MMP) inhibitors. Among all classes of MMP inhibitors, hydroxamates are important in that their zinc-binding group CONHOH makes them a bidentate ligand to act with any metal-containing enzyme. Most of the MMP inhibitors developed by pharmaceutical companies belong to this category of compounds. The

省略

Hydroxamic Acids as Histone Deacetylase Inhibitors, inhibitors. One product, SAHA is already approved and more than ten different chemical entities are in various clinical stages. A detailed discussion about compounds from various classes like phenyloxopropenyl, amidopropenyl analogues, spiropiperidines, biphenyl/arylamide/styrenyl, tetrahydroisoqui

neutralize

Hydroxamates as Ribonucleotide Reductase Inhibitors,rs act as anticancer agents. The initial sections present a background about hydroxamic acids, role of RR inhibitors as anticancer agents, and information on three-dimensional structure of RR. The remaining sections, discuss the mode of action of these compounds and their progress in computer-aided

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Hydroxamic Acid Derivatives as Potential Anticancer Agents, strong affinity toward histone deacetylase, matrix metalloproteinases, human epidermal growth factor receptor-2, and tumor necrosis factor alpha converting enzyme. These enzymes play crucial roles in the pathogenesis of cancer and are attractive targets for the development of new anticancer agents.

APO

NUDGE

Hydroxamic Acids as Inhibitors of Urease in the Treatment of , Infections,esis of peptic ulcer and in the development of gastric carcinoma. It produces a nickel-dependent enzyme called urease which catalyzes the hydrolysis of urea to produce ammonia and carbamate. This ammonia produced by urease elevates the level of pH in the stomach, breaks gastric mucus, inhibits the c

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