Titlebook: Human Sleep; Research and Clinica Wallace B. Mendelson Book 1987 Plenum Publishing Corporation 1987 adenosine.alcoholism.central nervous sy

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Pharmacology and Neurotransmitters in SleepThe amount of available transmitter can be decreased by compounds that inhibit its synthesis. Drugs that bind to the neurotransmitter receptor may act as agonists or antagonists and, hence, may be used to characterize function.

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Narcolepsy and Disorders of Excessive Sleepinesst and short duration, recurring at more or less close intervals.” As Zarcone (1973) points out, characters with symptoms suggestive of narcolepsy have appeared in many famous works of fiction, including Eliot’s Silas Marner, Poe’s “The Premature Burial,” and Melville’s ..

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in which he conceived of neurotransmitters communicating across the synapse. He quickly made notes, but in the morning he could not understand his scribbles. The following night, the dream came again. He wrote down his thoughts more carefully and, the next day, conducted the crucial experiment that

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An Introduction to Sleep Studiescal activity was derived from neuronal tissue, that it responded to sensory stimulation, and that abnormal discharges occurred during epileptic seizures (Berger, 1929, 1938). He used the term electroencephalogram (EEG) to refer to his recordings of this electrical activity.

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Alcohol, Alcoholism, and the Problem of Dependenceme evidence that a disorder of sleep stage regulation may be involved in ethanol withdrawal syndromes. Each of these areas will be discussed here, in terms of knowledge gained from animal studies and effects of ethanol on sleep in normal volunteers and alcoholics.