| 書目名稱 | Human Retroviral Infections | | 副標(biāo)題 | Immunological and Th | | 編輯 | Kenneth E. Ugen,Mauro Bendinelli,Herman Friedman | | 視頻video | http://file.papertrans.cn/430/429426/429426.mp4 | | 叢書名稱 | Infectious Agents and Pathogenesis | | 圖書封面 |  | | 描述 | The discovery of the human T cell leukemia virus type I in the late 1970s heralded a new era in retrovirology. For the first time, it was demonstrated that a retrovirus could play a role in the development of a human disease, in this case adult T cell leukemia (ATL). Several years later, the acquired immunodeficiency syndrome (AIDS) epidemic began, and it was dem- strated that a retrovirus, originally designated the human T cell lymp- tropic virus type 3, was the causal agent of this syndrome. This virus, later named the human immunodeficiency virus type 1 (HIV-1), has since been extensively studied in terms of its pathogenesis as well as its ability to elicit immune responses. In that time, a tremendous amount of information has been obtained about the virus. Although recent drug regimens have been useful in significantly lowering viral loads and perhaps maintaining an asymptomatic state among individuals infected with HIV-1, an established “cure” for AIDS eludes us. In addition, the effective drug therapies are very expensive, and are not available to infected people in the third world, where greater than 90% of new infections occur. Furthermore, the development of viral resistan | | 出版日期 | Book 2002 | | 關(guān)鍵詞 | AIDS; Chemokine; Virus; gene therapy; infection; infections; vaccine; viral infection; infectious diseases | | 版次 | 1 | | doi | https://doi.org/10.1007/b111099 | | isbn_softcover | 978-1-4757-8168-7 | | isbn_ebook | 978-0-306-46819-3Series ISSN 1075-1289 | | issn_series | 1075-1289 | | copyright | Springer Science+Business Media New York 2002 |
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