Titlebook: Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer; Daniel L. Miller,M. Sharon Stack Book 2015 Springer International Publishing S

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Mutational Profile of HPV-Positive HNSCC,V). Focusing on next-generation sequencing studies, the differences between the mutations detected in HPV-positive HNSCC and HPV-negative HNSCC were compared. The low frequency of TP53 mutations in HPV-positive HNSCC and the link between HPV and TP53 are reviewed. A comparison of gene mutations sugg

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Differences and Similarities Between HPV-Associated OPSCC and Cervical Cancer,hough traditionally associated with cervical cancer, HPV infection has been more recently implicated in the pathogenesis of oropharyngeal squamous cell carcinomas (OSCCs). HPV+OSCC has emerged as a distinct entity in terms of etiology, biology, and clinical behavior. The model of cervical cancer cou

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HPV and Radiation Sensitivity,roved outcomes compared to those with traditional tobacco/alcohol associated head and neck cancers. These improved outcomes are likely multifactorial. In this chapter, we review the evidence for increased sensitivity to radiation playing an important role in the improved outcomes of these patients.

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