Titlebook: Human Herpesviruses; Yasushi Kawaguchi,Yasuko Mori,Hiroshi Kimura Book 2018 Springer Nature Singapore Pte Ltd. 2018 Herpes simplex virus.V

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Antiviral Drugs Against Alphaherpesvirus varicella-zoster virus infection, and the orally available prodrugs, valacyclovir and famciclovir, have improved antiviral treatment compliance. Acyclovir and penciclovir are phosphorylated by viral thymidine kinase and are incorporated into the DNA chain by viral DNA polymerase, resulting in chain

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Vaccine Development for Varicella-Zoster Virushighly safe and effective profiles; however, worldwide herd immunity against VZV has not yet been established and it is far from eradication. Despite the successful reduction in the burden of VZV-related illness by the introduction of the vaccine, some concerns about vOka critically prevent worldwid

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Glycoproteins of HHV-6A and HHV-6Bell tropism is one of their striking differences, which is partially because of the difference in their entry machinery. Many glycoproteins of HHV-6A/B have been identified and analyzed in detail, especially in their functions during entry process into host cells. Some of these glycoproteins were un

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Betaherpesvirus Virion Assembly and Egressfrom infected cells, survive in the extracellular environment during transmission, recognize and then trigger entry of appropriate target cells, and disassemble in an orderly manner during initiation of a new infection. The betaherpesvirus subfamily includes four human herpesviruses (human cytomegal

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Chromosomal Integration by Human Herpesviruses 6A and 6BA and HHV-6B can integrate their genomes into host chromosomes as one way to establish latency. Viral integration takes place near the subtelomeric/telomeric junction of chromosomes. When HHV-6 infection and integration occur in gametes, the virus can be genetically transmitted. Inherited chromosoma