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Titlebook: Human Hemoglobin Genetics; George R. Honig,Junius G. Adams Book 1986 Springer-Verlag/Wien 1986 genetics

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發(fā)表于 2025-3-21 19:10:21 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Human Hemoglobin Genetics
編輯George R. Honig,Junius G. Adams
視頻videohttp://file.papertrans.cn/430/429216/429216.mp4
圖書封面Titlebook: Human Hemoglobin Genetics;  George R. Honig,Junius G. Adams Book 1986 Springer-Verlag/Wien 1986 genetics
描述The discovery in the late 1940‘s that sickle cell anemia is a "molecular disease" of hemoglobin was the crucial advance that gave birth to the scientific discipline of human molecular genetics. In subsequent years, with the continued expansion of knowledge about the biology and genetics of the hemoglobins, and particularly as a result of the characterization of the very large numbers of globin gene mutations, the human hemoglobin system has remained as the premier model of gene expression at the molecular level in man. With the recent explosion of new information about the genetic properties of the hemoglobins, it appears inevitable that this gene system will continue to occupy a unique position in human molecular genetics for many years in the future. Hemoglobin genetics has also recently come of age as a diagnostic and clinical discipline. The heightening of public awareness in recent years about sickle cell disease, thalassemia, and other inherited disorders has brought increasing demands for carrier detection services as well as for genetic counseling and education. The more recent development of prac- tical and reliable methods for the antenatal diagnosis of hemoglobin dis- or
出版日期Book 1986
關(guān)鍵詞genetics
版次1
doihttps://doi.org/10.1007/978-3-7091-8798-2
isbn_softcover978-3-7091-8800-2
isbn_ebook978-3-7091-8798-2
copyrightSpringer-Verlag/Wien 1986
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發(fā)表于 2025-3-21 21:32:58 | 只看該作者
he scientific discipline of human molecular genetics. In subsequent years, with the continued expansion of knowledge about the biology and genetics of the hemoglobins, and particularly as a result of the characterization of the very large numbers of globin gene mutations, the human hemoglobin system
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The Globin Gene Mutations,h emphasis on the mode of expression of their mutant genes. These disorders have been reviewed extensively in several recent texts (Lehmann and Huntsman, 1974; Serjeant, 1974; Schwartz, 1980; Weatherall and Clegg, 1981).
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發(fā)表于 2025-3-22 22:24:20 | 只看該作者
The Geographic Distribution of Globin Gene Variation,relatively high frequency, but only in individuals within highly isolated populations. On the other hand, the group that includes Hb S, Hb C, Hb E, and the thalassemias includes enormous numbers of people and extends over a very wide geographical area. (For a more detailed account see Bowman, 1983, and Winter, 1985).
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發(fā)表于 2025-3-23 03:39:40 | 只看該作者
Approaches to the Treatment of the Hemoglobin Disorders,ffer, as well as their often extensive needs for transfusions and other forms of medical care, have stimulated major efforts toward the development of more effective forms of therapy for these conditions.
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978-3-7091-8800-2Springer-Verlag/Wien 1986
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