| 書目名稱 | Human Epigenomics | | 編輯 | Carsten Carlberg,Ferdinand Molnár | | 視頻video | http://file.papertrans.cn/430/429143/429143.mp4 | | 概述 | Is the first textbook on epigenomics with a clear focus on human.Links epigenomics to numerous disciplines, such as embryogenesis, nutrition and neuroscience.Discusses impact of epigenomics in health | | 圖書封面 |  | | 描述 | .The term .epigenetics. describes regulatory and information storing mechanisms of specific genes that do not involve any change of their DNA sequence. Epigenetics is closely related to the extensively folded state, in which the genome is packaged, known as chromatin. New genomic tools nowadays allow the genome-wide assessment of, for example, chromatin states and DNA modifications, and led to the discovery of unexpected new epigenetic principles, such as epigenomic memory. This was the start of the field of .epigenomics., the relation of which to human health and disease is discussed in this textbook...This book aims to summarize, in a condensed form, the role of epigenomics in defining chromatin states that are representative of active genes (euchromatin) and repressed genes (heterochromatin). Moreover, this book discusses the principles of gene regulation, chromatin stability, genomic imprinting and the reversibility of DNA methylation and histone modifications. This information should enable a better understanding of cell type identities and will provide new directions for studies of, for example, cellular reprograming, the response of chromatin to environmental signals and epi | | 出版日期 | Textbook 2018 | | 關(guān)鍵詞 | Epigenomics in Cancer; Epigenomics in Nutrition; Histone Modification; Chromatin Structure; Chromatin Mo | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-10-7614-5 | | isbn_softcover | 978-981-13-5660-5 | | isbn_ebook | 978-981-10-7614-5 | | copyright | Springer Nature Singapore Pte Ltd. 2018 |
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