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Titlebook: Cancer Cell Lines Part 1; John R. W. Masters,Bernhard Palsson Book 1999 Springer Science+Business Media Dordrecht 1999 biology.cancer.canc

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書目名稱Cancer Cell Lines Part 1
編輯John R. W. Masters,Bernhard Palsson
視頻videohttp://file.papertrans.cn/430/429039/429039.mp4
叢書名稱Human Cell Culture
圖書封面Titlebook: Cancer Cell Lines Part 1;  John R. W. Masters,Bernhard Palsson Book 1999 Springer Science+Business Media Dordrecht 1999 biology.cancer.canc
描述Continuous cell lines derived from human cancers are the most widely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions of fundamental importance to the relevance of human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation? 2. Do the cell lines accurately represent the histopathology of the original tumors? 3. Do the cell lines accurately represent the molecular genetics of this type of cancer? The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor ar
出版日期Book 1999
關(guān)鍵詞biology; cancer; cancer research; cell; cell culture; cell lines; melanoma; mesothelioma; tumors
版次1
doihttps://doi.org/10.1007/0-306-46872-7
isbn_softcover978-94-017-3824-8
isbn_ebook978-0-306-46872-8Series ISSN 1389-2142
issn_series 1389-2142
copyrightSpringer Science+Business Media Dordrecht 1999
The information of publication is updating

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