Titlebook: How Free Cationic Polymer Chains Promote Gene Transfection; Yue Yanan Book 2013 Springer International Publishing Switzerland 2013 Cyclode

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https://doi.org/10.1007/978-3-319-00336-8Cyclodextrin-Based Polymers; Endocytic Vescicles; Endocytic-Vesicle-to-Endolysosome Pathway; Free Polyc

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How Free Cationic Polymer Chains Promote Gene Transfection978-3-319-00336-8Series ISSN 2190-5053 Series E-ISSN 2190-5061

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Yue YananNominated as an outstanding Ph.D. thesis by the Chinese University of Hong Kong.Addresses and elucidates a critical but long overlooked question on non-viral gene delivery.Greatly deepens our understa

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Book 2013determines that those uncomplexed and cationic polymer chains free in the solution mixture of polymer and DNA facilitate and promote gene transfection. Furthermore, by using a combination of synthetic chemistry, polymer physics and molecular biology, Yue confirms that it is those cationic polymer ch

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Introduction and Background,e led to the recognition of numerous diseases-relating genes. It has been gradually and generally realized that development of safe, efficient and controllable gene-delivery vectors is now a bottleneck in clinical applications.

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