Titlebook: High-Throughput Screening Assays in Toxicology; Hao Zhu,Menghang Xia Book 2016 Springer Science+Business Media New York 2016 Chemical toxi

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CurveP Method for Rendering High-Throughput Screening Dose-Response Data into Digital Fingerprintscan be a part of HTS data analysis or can be used as input for a broad spectrum of computational applications, such as Quantitative Structure-Activity Relationship (QSAR) modeling, computational toxicology, bio- and cheminformatics.

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High-Throughput and High-Content Micronucleus Assay in CHO-K1 Cellsfragment of chromosome can lead to formation of micronuclei (MNi). The in vitro micronucleus assay can be conducted using nuclear dyes with high-content imaging platforms. This chapter describes the cytochalasin block method of measuring micronuclei in CHO-K1 cell lines.

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Hao Zhu,Menghang XiaIncludes cutting-edge methods and protocols for HTS assays to examine toxicity.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the exp

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978-1-4939-8171-7Springer Science+Business Media New York 2016

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https://doi.org/10.1007/978-1-4939-6346-1Chemical toxicity testing; HTS assays; Computational techniques; In vitro and In vivo; Toxicology assess

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