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Titlebook: Hepatitis B Virus in Human Diseases; Yun-Fan Liaw,Fabien Zoulim Book 2016 Springer International Publishing Switzerland 2016 HBV carcinoge

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發(fā)表于 2025-3-21 19:00:32 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Hepatitis B Virus in Human Diseases
編輯Yun-Fan Liaw,Fabien Zoulim
視頻videohttp://file.papertrans.cn/426/425703/425703.mp4
概述Provide a concise yet comprehensive summary of the current status of the field.A major emphasis is made on the management of antiviral therapy and the recent international guidelines for the treatment
叢書名稱Molecular and Translational Medicine
圖書封面Titlebook: Hepatitis B Virus in Human Diseases; Yun-Fan Liaw,Fabien Zoulim Book 2016 Springer International Publishing Switzerland 2016 HBV carcinoge
描述.This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for students, clinicians, and researchers with an interest in hepatitis B.? The book reviews new data about basic and translational science including the viral life cycle, the immunopathogenesis of virus induced chronic hepatitis, the mechanism of virus induced liver cancer, and their potential applications for the clinical management of patients. The clinical aspects of this chronic viral infection?are reviewed in detail?with important chapters on the global epidemiology, the natural history of the disease, co-infections with its satellite virus HDV or HIV, and?management of special patient populations. A major emphasis?is made on the management of antiviral therapy and the recent international guidelines for the treatment of hepatitis B. Finally, the book reviews the current state of the art regarding immunoprophylaxis to prevent the spread of the virus and its major clinical consequences. The new advances and perspectives in the development of improved antiviral treatments?are also discussed..Hepatitis B Virus in Human Diseases. will serve as a very useful resource f
出版日期Book 2016
關(guān)鍵詞HBV carcinogenesis; HBV immunopathogenesis; HDV on HBV infection; Immunoprophylaxis of HBV; Translationa
版次1
doihttps://doi.org/10.1007/978-3-319-22330-8
isbn_softcover978-3-319-36308-0
isbn_ebook978-3-319-22330-8Series ISSN 2197-7852 Series E-ISSN 2197-7860
issn_series 2197-7852
copyrightSpringer International Publishing Switzerland 2016
The information of publication is updating

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Experimental Models: Cell Culture and Animal Models,nd more innovative experimental models, placing emphasis on the strength of new in vitro and in vivo infection systems that may serve as tools for elucidating still unknown steps of HBV biology, as well as for preclinical drug evaluation.
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發(fā)表于 2025-3-22 16:33:03 | 只看該作者
Hepatitis B Virus Immunopathogenesis,fected by the anatomical conditions that characterize the normal or diseased liver—have been recently elucidated. This chapter discusses past and recent scientific achievements related to HBV immunopathogenesis.
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發(fā)表于 2025-3-22 18:01:52 | 只看該作者
Pathobiology of Hepatitis B Virus-Induced Carcinogenesis,es chromatin dynamics at specific gene loci. Compared with tumors associated with other risk factors, HBV-related tumors have a higher rate of chromosomal alterations, p53 inactivation by mutations and overexpression of fetal liver/hepatic progenitor cells genes. The wnt/β-catenin pathway is also of
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Hepatitis B Virus: Persistence and Clearance,nd, especially, CTL-stimulated turnover should lead to genetic narrowing of the hepatocyte population as the patient ages. This process will be further accelerated if any hepatocyte mutations facilitate escape from antiviral CTLs, or provide a growth advantage. Finally, the association of genetic na
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Hepatitis Delta Virus: Virology and Replication, of HDV RNPs is dependent upon the assistance of the HBV envelope proteins and their intrinsic capacity to assemble lipoprotein vesicles—or subviral particles—in HBV-infected hepatocytes. Coated with the HBV envelope proteins, the exported HDV virions can survive in the extracellular space and enter
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