Titlebook: Hemostasis and Thrombosis; Methods and Protocol Emmanuel J. Favaloro,Giuseppe Lippi Book 2017 Springer Science+Business Media LLC 2017 Coag

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Preanalytical Issues in Hemostasis and Thrombosis Testingosis, prognostication, and therapeutic monitoring. Due to this crucial role in modern medicine, hemostasis tests should be carried out at their highest degree of quality, thus encompassing standardization and monitoring of all phases of the testing process. It is now clearly established that the pre

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D-Dimer Testing: Laboratory Aspects and Current Issuesting has significantly decreased the number of radiological investigations in this clinical scenario. D-dimer testing also plays an important role in the diagnostic process of the systemic coagulation disorders, especially disseminated intravascular coagulation in conjunction with other coagulation

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An Overview of Thrombophilia and Associated Laboratory Testinger of putative conditions interplay and finally contribute to propel the individual risk over a certain degree, so ultimately culminating in the development of venous occlusive disorders. Thrombophilia is commonly defined as a propensity to develop venous thromboembolism on the basis of an underlyin

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Laboratory Testing for Activated Protein C Resistance (APCR)s results in an increased risk of venous thrombosis, including deep vein thrombosis and pulmonary embolism. Protein C is a natural anticoagulant that is synthesized in the liver and is activated to APC via proteolysis. APC then degrades Factors Va and VIIIa. APCR describes the reduced inability of A

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Assessment of Hereditary Thrombophilia: Performance of Protein C (PC) Testingess by neutralizing the procoagulant activities of factors V and VIII in the presence of the cofactor Protein S. PC is a major regulator of the coagulation process. The clotting based Protein C assay, the protocol described in this chapter, quantitates the amount of functional PC present in the spec