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Titlebook: Helicobacter pylori and Gastric Cancer; Steffen Backert Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive license

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發(fā)表于 2025-3-21 18:45:51 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Helicobacter pylori and Gastric Cancer
編輯Steffen Backert
視頻videohttp://file.papertrans.cn/426/425502/425502.mp4
概述Discusses the underlying molecular mechanisms of Helicobacter pylori-induced gastric cancer.Provides strategies for clinical management and treatment of gastric cancer.Reviews how Helicobacter pylori
叢書名稱Current Topics in Microbiology and Immunology
圖書封面Titlebook: Helicobacter pylori and Gastric Cancer; Steffen Backert Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive license
描述.This volume explores in detail the molecular biology, genetics and immunology of the bacterium .Helicobacter?pylori .that causes serious gastric diseases such as gastric cancer. The book provides in-depth insights into the mechanisms of .H.?pylori.-induced pathogenicity, gives an overview of how the bacterium colonizes the human gut, how it manages to persist in the body and which factors play a role in the development of .H. pylori.-induced gastric cancer. Furthermore, the interaction between the Gram-negative bacterium and the human gut microbiome is explored, and clinical management and treatment strategies to combat gastric cancer are discussed..Helicobacter pylori .is an extremely successful pathogen that persistently colonizes the gut of about 50% of the world’s population. .H.?pylori. and its human host share a long co-evolutionary relationship that dates back for at least last 100,000 years and possibly longer. Infection by thisbacterium is a high-risk factor for the development of gastric diseases, including gastric cancer. Gastric cancer is associated with high morbidity and mortality and represents the 5th most common malignant tumour and the 4th leading cause of cancer
出版日期Book 2023
關(guān)鍵詞oncoprotein; type IV secretion system; pathogenesis; virulence; Gastric adenocarcinoma; Helicobacter pylo
版次1
doihttps://doi.org/10.1007/978-3-031-47331-9
isbn_softcover978-3-031-47333-3
isbn_ebook978-3-031-47331-9Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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Impact of the , Oncoprotein CagA in Gastric Carcinogenesis,rror-free homologous recombination-mediated DNA double-strand breaks (DSBs) by inhibiting cytoplasmic-to-nuclear localization of the BRCA1 tumor suppressor. This causes genomic instability that leads to the accumulation of excess mutations in the host cell genome, which may underlie hit-and-run gast
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