| 書目名稱 | Heat Shock Proteins of Malaria |
| 編輯 | Addmore Shonhai,Didier Picard,Gregory L. Blatch |
| 視頻video | http://file.papertrans.cn/426/425021/425021.mp4 |
| 概述 | Refreshed second edition.Addresses fundamental research with an emphasis on anti-malarials and therapeutic interventions.Details on druggability of heat shock proteins appeal to drug discovery experts |
| 叢書名稱 | Advances in Experimental Medicine and Biology |
| 圖書封面 |  |
| 描述 | This new edition describes the role of heat shock proteins in the life cycle of malaria parasites, particularly in the context of intracellular parasite stages. Thoroughly revised, this work provides a general introduction to the structural and functional features of heat shock proteins with a special focus on their role as molecular chaperones in ensuring protein quality control. The emphasis is on the heat shock protein families from .Plasmodium falciparum., and their role in proteostasis and the development of malaria pathology. Moreover, the authors explore the latest prospects of targeting heat shock proteins in antimalarial drug discovery either directly or in combination therapies..Readers will experience a functional analysis of the individual families of heat shock proteins and their cooperation in functional networks, including both the parasite-resident proteome and the exportome released into host cells during intracellular stages. Subcellular and extracellular organelles such as the apicoplast and the Maurer’s Clefts associated with .Plasmodium. species are discussed in detail. The book highlights the role of heat shock proteins in the development and function of these |
| 出版日期 | Book 2021Latest edition |
| 關(guān)鍵詞 | Cell Stress; Chaperones; Co-chaperones; Drug Development; Heat Shock Protein; Immunmodulation; Malaria; Mal |
| 版次 | 2 |
| doi | https://doi.org/10.1007/978-3-030-78397-6 |
| isbn_softcover | 978-3-030-78399-0 |
| isbn_ebook | 978-3-030-78397-6Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
|Archiver|手機(jī)版|小黑屋|
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