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Titlebook: Heat Shock Proteins in Human Diseases; Alexzander A. A. Asea,Punit Kaur Book 2021 The Editor(s) (if applicable) and The Author(s), under e

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發(fā)表于 2025-3-21 19:39:11 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱(chēng)Heat Shock Proteins in Human Diseases
編輯Alexzander A. A. Asea,Punit Kaur
視頻videohttp://file.papertrans.cn/426/425013/425013.mp4
概述Provides the most comprehensive review of contemporary knowledge on the role of HSP in signaling pathways relevant to a number of diseases.Contains chapters contributed by specialists from key basic a
叢書(shū)名稱(chēng)Heat Shock Proteins
圖書(shū)封面Titlebook: Heat Shock Proteins in Human Diseases; Alexzander A. A. Asea,Punit Kaur Book 2021 The Editor(s) (if applicable) and The Author(s), under e
描述.The book?.Heat Shock Proteins in Cancer Therapeutics?.provides the most comprehensive review on contemporary knowledge on the role of HSP in various types of cancer therapeutics. Using an integrative approach, the contributors provide a synopsis of the most current updates on the state of HSP in cancer therapeutics..The heat shock response pathway is a highly conserved cellular process. Heat shock factors are a master transcriptional regulator responsible for expression of several important heat shock proteins, which can effectively protect critical client proteins from misfolding and degradation, thus maintaining intracellular integrity under stressed conditions. Recent studies have demonstrated the direct connections between heat shock response players and tumor cell survival, validating heat shock response players as novel molecular targets in anticancer treatment. Although many hurdles in clinical application still need to be effectively addressed, such as undesirable drug toxicity and off target effects; narrow therapeutic window; poor PK/PD profiles, etc. Recent reports on synergistic drug combination, advanced prodrug design, smart nanoparticle packaging, and RNA aptamer se
出版日期Book 2021
關(guān)鍵詞Chaperone; Cancer; Inflammatory Diseases; Immunity; Molecular Therapy
版次1
doihttps://doi.org/10.1007/978-3-030-62289-3
isbn_softcover978-3-030-62291-6
isbn_ebook978-3-030-62289-3Series ISSN 1877-1246 Series E-ISSN 1877-1254
issn_series 1877-1246
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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Chaperonin Hsp60 and Cancer Therapies,and distribution alterations in cells and tissues accompanying tumor initiation and progression. We also discuss the potential of HSP60-based anti-cancer therapies that are currently being investigated.. Journals and data bases were surveyed, and pertinent works were chosen for discussion.. The data
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Heat Shock Proteins in Atrial Fibrillation,ive role on atrial cardiomyocytes during AF involving electrical remodeling, structural remodeling, inflammatory processes and oxidative stress. Furthermore, potential implications of HSP in the management of AF are also briefly discussed. HSP may serve as the predictors of AF type and recurrence in
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Roles of HSP on Antigen Presentation,0 in the MHC-I pathway and the functions of HSP70 in the MHC-II pathway are being elucidated. However, several unsolved questions have still remained. For example, does the same mechanism function in all antigen-presenting cells? Is there specificity for antigen proteins in the HSPs? In addition, th
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Abdullah Hoter,Aseel Othman Alsantely,Edreese Alsharaeh,George Kulik,Islam M. Saadeldin 1.2% vs 0%). Other factors previously implicated in AD were not significantly more common in AD than in CI (head trauma in 4.2% vs 8.3%; peptic ulcers (presumably with aluminum-containing antacid use) in 5.8% vs 8.3%, alcoholism in 0.7% vs 0%, job-related toxic exposures in 1.5% vs 0%, and thyroid
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