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Titlebook: Haploidentical Stem Cell Transplantation; An Emerging Treatmen Taner Demirer Book 2017 Springer International Publishing AG 2017 CD34+.Dono

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發(fā)表于 2025-3-21 17:41:25 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Haploidentical Stem Cell Transplantation
副標(biāo)題An Emerging Treatmen
編輯Taner Demirer
視頻videohttp://file.papertrans.cn/425/424084/424084.mp4
概述Authors are worldwide experts in the field and provide international perspectives and expertise.A rapidly developing modality; this topic has not yet appeared in many books but mostly in journal artic
叢書名稱Stem Cell Biology and Regenerative Medicine
圖書封面Titlebook: Haploidentical Stem Cell Transplantation; An Emerging Treatmen Taner Demirer Book 2017 Springer International Publishing AG 2017 CD34+.Dono
描述.This book discusses the aspects of haploidentical transplants and will shed light on the debates and questions on this burgeoning field and timely topic. Donor selection, graft failure, minimal CD34+ cell requirement, and conditioning regimens used for haploidentical transplants will be written by expert authors dealing with this type of transplants. Approximately one third of the books‘ chapters cover logic and basic aspects; the remaining two thirds of the book discuss clinical aspects, outcomes, and future perspectives, thus providing a?comphrensive discussion of the topic.?Haploidentical transplantation is extremely timely, rapidly-changing area and increasing its use will decrease the need for time-consuming, expensive, unrelated donor search. Moreover, .Haploidentical Stem Cell Transplantation.?brings a set of clear answers to questions of feasibility, advantages over unrelated transplants, cost effectivity and outcome..?.
出版日期Book 2017
關(guān)鍵詞CD34+; Donor Selection; Graft Failure; Leukemia; Lymphoma
版次1
doihttps://doi.org/10.1007/978-3-319-65319-8
isbn_softcover978-3-319-87999-4
isbn_ebook978-3-319-65319-8Series ISSN 2196-8985 Series E-ISSN 2196-8993
issn_series 2196-8985
copyrightSpringer International Publishing AG 2017
The information of publication is updating

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發(fā)表于 2025-3-21 20:17:55 | 只看該作者
Donor Selection and Cell Dose in Haploidentical SCT,easy way to control the bidirectional alloreactivity, a problem that once was a major hassle to the advance of this procedure. Currently haploidentical stem cell transplantation represents the default option for alternative donor selection for some of the largest transplant centers around the world.
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發(fā)表于 2025-3-22 05:44:41 | 只看該作者
Toxicity of Conditioning Regimens in Haploidentical SCT,antations and even, the drugs are the same for both transplantation types. The advances in the haploidentical HSCT is mostly the result of the usage of post transplantation cyclophosphamide (PT-CY) as GVHD prophylaxis. At first PT-CY was used only in haplo setting however, today many centers use PT-
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Graft Versus Leukemia (GvL), Graft Versus Lymphoma Effect in Haploidentic SCT, inability to measure GvL in any other way than by assessing the reduction in relapse incidence with versus without an allogeneic stem cell transplant. The strength of GvL is probably enhanced in haploidentical SCT as compared to SCT from other donors given the added alloreactivity due to the HLA mi
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Applications of Haploidentical SCT in Patients with Non-malignant Diseases,n patients with non-malignant diseases, who are lacking a HLA identical sibling or compatible unrelated donor. T-cell depletion by CD34+ cell selection resulted in relative high risk of graft failure with exception of SCIDs. Further refinement has been reported for selected depletion of α/β T-cells
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