Titlebook: Handbook on Artificial Intelligence-Empowered Applied Software Engineering; VOL.2: Smart Softwar Maria Virvou,George A. Tsihrintzis,Lakhmi

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Elamin Abderrahim,Nada Matta,Hassan Atifisites, and the respective writers and erasers remains challenging. The use of recently developed mass spectrometric methods helps to further characterize the ADP-ribosylome and its regulatory enzymes under different conditions and in different cell types. Validation of these findings may be achieved

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in-like family (ARTD) of ADP-ribosyltransferases (aka PARP enzymes). It involves the transfer of a single residue of ADP-ribose (ADPr) from the cofactor NAD. onto substrate proteins. Although 12 of the 17 members of the ARTD family have been defined as mono-ARTDs in in vitro assays, relatively littl

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Joey Sherrill,Yiu-Kai Ngbstrates accepting ADP-ribose modification, a recent report demonstrated biological role for DNA ADP-ribosylation as well. The conserved macrodomain fold of several known hydrolyses was found to possess de-ADP-ribosylating activity and the ability to hydrolyze (reverse) ADP-ribosylation. Here we sum

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Vijayalakshmi Ramasamy,Mourya Reddy Narasareddygari,Gursimran S. Walia,Andrew A. Allen,Debra M. Duke types. The ARTC2 enzymes catalyze mono-ADP-ribosylation of arginine residues in the extracellular domain of membrane proteins or secretory proteins. In this chapter we provide protocols to monitor the expression and activity of ARTCs on the cell membrane of living cells and in soluble form in biolo

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— in der Behandlung von Kindern mit ADS/ADHS den besten Erfolg verspricht. Genaueren Aufschluss gab erst die Multimodal Treatment of ADS/ADHS (MTA)-Studie, in der die Wirksamkeit verschie-dener Settings über mittlerweile 24 Monate miteinander verglichen wurde.

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Aspassia Daskalopulu,Lefteri H. Tsoukalas,Dimitrios Bargiotas Signifikante Schmerzen und funktionelle Einschr?nkungen sind die wesentlichen klinischen Indikationen für die Implantation einer Hüfttotalendoprothese. Hüftgelenkerkrankungen, die mit den entzündlichen Ver?nderungen vergesellschaftet sind, zeigen oftmals eine schlechtere Knochenqualit?t. Dies erfor

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umatischen Kubitalarthrose. Steife und Instabilit?t, mono- und polyartikul?rer Befall, Anforderungen an den Prothesengebrauch charakterisieren unter anderem die Breite des Symptomenspektrums. Daneben sind es die Knochen- und Muskelverluste, die die Tumorendoprothetik am Ellenbogen kennzeichnen..Indi