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Titlebook: Handbook of Neurotoxicity; Richard M. Kostrzewa Living reference work 20210th edition Neurotoxicity.Neurtoxins.Neurodegeneration.Neuropro

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發(fā)表于 2025-3-21 19:01:10 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Handbook of Neurotoxicity
編輯Richard M. Kostrzewa
視頻videohttp://file.papertrans.cn/422/421771/421771.mp4
概述Guides readers through neurotoxins and neurotoxicity in Neuroscience.Describes the relationship between specific neurotoxins and neurodegenerative disorders.Provides up-to-date research on excitotoxic
圖書封面Titlebook: Handbook of Neurotoxicity;  Richard M. Kostrzewa Living reference work 20210th edition  Neurotoxicity.Neurtoxins.Neurodegeneration.Neuropro
描述This handbook is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments – to understand mechanisms associated with toxin use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities. Neuroprotection is approached in different manners including?those 1) afforded by therapeutic agents – clinical and preclinical; or 2) by non-drug means, such as exercise. The amorphous term ‘neurotoxin’ is discussed in terms of the possible eventuality of a neuroprotectant producing an outcome of excess neuronal survival and a behavioral spectrum that might produce a dysfunction – akin to a neurotoxin’s effect. This new edition significantly expands on the information provided in the first edition, providing the latest research in neurotoxicity and highlighting the relationship between specificneurotoxins and the neurodegenerative disorders they can cause. It also includes new sections on the neurotoxicity of heavy metals, fungi, and snake venom. The Handbook of Neurotoxicity is thus an instructi
出版日期Living reference work 20210th edition
關(guān)鍵詞Neurotoxicity; Neurtoxins; Neurodegeneration; Neuroprotection; Parkinson‘s Disease; Alzheimer‘s Disease; D
doihttps://doi.org/10.1007/978-3-030-71519-9
isbn_ebook978-3-030-71519-9
The information of publication is updating

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發(fā)表于 2025-3-21 22:52:08 | 只看該作者
Manganese Neurotoxicity,een broadly used in industry due to its chemical properties. Because of this wide usage, Mn has become an important environmental toxin. Since this metal has been associated to a parkinsonian-like syndrome called manganism, it has been extensively studied, with a major focus on its effects on neuron
板凳
發(fā)表于 2025-3-22 02:05:56 | 只看該作者
,Links Between Paraquat and Parkinson’s Disease,milial PD. However, the majority of cases are sporadic and their origin(s) still remain undetermined. The environment is a key contributor to human health and disease. Epidemiological evidence suggests that environmental factors and/or mutations in genes play a role in the etiology of neurodegenerat
地板
發(fā)表于 2025-3-22 07:41:28 | 只看該作者
-Methyl-(,)salsolinol and Enzymes Involved in Enantioselective Biosynthesis, Bioactivation, and Tox of Parkinson’s disease has been intensively investigated. The Pictet-Spengler reaction nonenzymatically produces racemic isoquinolines, but the predominant occurrence of (.).enantiomers in the human brain and the selective toxicity suggest the involvement of enantio-specific enzyme system. This pap
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發(fā)表于 2025-3-22 10:30:24 | 只看該作者
,Iron Neurotoxicity in Parkinson’s Disease,, neurons have expeditious mechanisms to ensure a readily available iron supply. However, several neurodegenerative diseases present dysregulation of iron homeostasis derived from mitochondrial dysfunction, inflammatory conditions, decreased glutathione levels, and oxidative damage, resulting in dow
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發(fā)表于 2025-3-22 13:14:29 | 只看該作者
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發(fā)表于 2025-3-22 19:27:54 | 只看該作者
,p75NTR: A Molecule with Multiple Functions in Amyloid-β Metabolism and Neurotoxicity,ch as neurofibrillary tangles, neuron loss, neurite degeneration, as well as cognitive dysfunction, are hallmarks of the disease. Until now, the pathogenesis of AD is not fully understood, and no disease-modifying interventions are currently available. Recent studies suggest that the neurotrophin re
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發(fā)表于 2025-3-23 00:19:44 | 只看該作者
Neurotrophic Therapy for ALS/MND,e, and injury. In the context of amyotrophic lateral sclerosis (ALS), it has long been hypothesized that . of neurotrophic growth factors . contributors to the disease that results in death of motor neurons. This has led to a considerable number of clinical trials undertaken involving neurotrophic t
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發(fā)表于 2025-3-23 04:55:36 | 只看該作者
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