Titlebook: Handbook of Chemical Biology of Nucleic Acids; Naoki Sugimoto Reference work 2023 Springer Nature Singapore Pte Ltd. 2023 DNA.RNA.Riboswit

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Traité d‘a(chǎn)ndrologie à l‘usage des cliniciensbiochemical studies. Knowledge of the structure and dynamics of nucleic acids is important not only for understanding biological mechanisms, but also for developing new therapeutics. NMR (Nuclear Magnetic Resonance) spectroscopy has been used for many years to determine the structure of nucleic acid

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D. Wallon,D. Campion,D. Hannequineral Z-DNA-binding proteins and Z-DNA-forming sequences in the genome have confirmed the biological relevance of Z-DNA. Over the last five decades, enormous scientific achievements have been made by outstanding scientists to reveal the chemical nature of Z-DNA and the role of Z-DNA and Z-DNA-binding

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https://doi.org/10.1007/978-3-642-49326-3fic human genomic locations of functional significance, such as telomeres, promoters, and replication initiation sites. They are involved in essential cellular processes, such as genome stability, gene transcription, and DNA replication. DNA G-quadruplexes readily form under physiologically relevant

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Siswantari Sijono,Susanto Zuhdiarea of research in telomere, gene regulation, and functional genomics research. Investigation of G-quadruplex structures associated with biological events is therefore essential to understanding the functions of these molecules. Antibodies and some small molecules have been used to investigate DNA

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Trajectory Analysis in Health Careraction between them at the atomic level is expected to provide valuable information for revealing the molecular mechanism responsible for the regulation of diverse biological processes through their interaction. Heme binds selectively to the 3′-terminal G-quartet of a parallel G-quadruplex DNA to f

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Trakls lyrische Einflüsse und Intertexteherapeutic agents to modulate gene expression or impede protein function by binding a specific RNA sequence or target protein but also in synthetic biology, particularly in the context of artificial genetic polymers (XNAs). In order to enable maximum scope for all . applications, it is pivotal for o

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,Der Kompromi? im Lichte des Rechts,cations in structure elucidation, synthetic genetics, and therapeutics, among others. This chapter explores the use of 2′-fluoroarabino nucleic acids (FANA) in the context of noncanonical nucleic acid structures, namely triple helices, G-quadruplexes, and i-motifs. For the last three decades, FANA h