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Titlebook: Haemostatic Drugs; A critical appraisal M. Verstraete Book 1977 Martinus Nijhoff, P.O.B. 442, The Hague, The Netherlands 1977 alcohol.blood

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書目名稱Haemostatic Drugs
副標(biāo)題A critical appraisal
編輯M. Verstraete
視頻videohttp://file.papertrans.cn/421/420438/420438.mp4
圖書封面Titlebook: Haemostatic Drugs; A critical appraisal M. Verstraete Book 1977 Martinus Nijhoff, P.O.B. 442, The Hague, The Netherlands 1977 alcohol.blood
描述clinical efficacy of haemostatic agents had to be published work and had to fulftl most of the following minimum requirements: (1) Quantitation ofthe measured blood loss was required, and not merely a clinical impression of the amount of blood lost, if the document pertained to a planned but ?open? clinical trial. (2) Only double-blind trials with random allocation of the placebo and experimental drug to preselected patients were considered suitable for discussion, if the blood loss had not been quantitated in a prospective trial. (3) Defmition and appropriate selection of patients admitted to the trial: all inclusion and exclusion criteria used to select patients had to be mentioned in detail. (4) Once included in the trial, patients could be withdrawn only on the basis of strict criteria for withdrawal which had been defined in advance. (5) A double-blind trial had to be continued for an adequate length of time if the haemostatic agent was being assessed in the prevention of bleeding in patients with a long lasting bleeding disorder . (6) A clear and detailed statistical analysis of the results was required. Moreover, a clear distinction between the therapeutic and prophylactic v
出版日期Book 1977
關(guān)鍵詞alcohol; blood; clinical trial; drug; drugs; patients; prevention; tissue
版次1
doihttps://doi.org/10.1007/978-94-010-1106-8
isbn_softcover978-90-247-2020-0
isbn_ebook978-94-010-1106-8
copyrightMartinus Nijhoff, P.O.B. 442, The Hague, The Netherlands 1977
The information of publication is updating

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,Report on a preparation of oxalic and malonic acids: Koagamin?,ly. In 1939 Steinberg and Brown claimed that oxalic acid accelerated the coagulation time. Steinberg and Brown in 1939 described beneficial effects in patients suffering from various defects of haemostasis. Herbst and Weinstein (1944) claimed acceleration of the bleeding time and of the capillary tu
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,Comments by the manufacturer of Dicynene?,as a brand name as far as I know. Earlier papers also refer to 141E, 141MD, the two laboratory numbers which it has had at various stages. Although some earlier workers considered that ethamsylate was related to Congo Red, it seems to me that there is very little resemblance between the chemistry of
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Comments on adrenochrome,und, i.e. an oxidation product of adrenaline. Early work suggested that adrenochrome could act as a‘promediator’ of the activity of adrenergic fibres (Derouaux and Roskam, 1939; Derouaux, 1941). Later work by Bacq and Derouaux (1950), however, showed that it was unlikely that an oxidized form of adr
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,Comments by the manufacturer of Premarin?,human clinical research. Thus the evaluation of any haemostatic agent is very difficult to assess, especially in some surgical procedures during which the blood loss is . minimal. In this present form, the review appears to deny the prophylactic or therapeutic usefulness of Premarin? Parenteral in t
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