書目名稱 | HLA and Disease Associations | 編輯 | Jawahar L. Tiwari,Paul I. Terasaki | 視頻video | http://file.papertrans.cn/421/420248/420248.mp4 | 圖書封面 |  | 描述 | The human leukocyte antigen (HLA) or tissue types are the products of a rapidly developing field of knowledge within the last 20 years. In the early stages of the research many investigators suspected the existence of a complex series of transplantation antigens, but it was widely believed that these antigens would not be well-defined even in this century. Yet in the last two decades as many as 124 different HLA antigens determined by at least 7 very closely linked genes located on the short arm of chromosome 6 have been identified and subsequently agreed upon by an international nomenclature committee. 1 Extensive international collaboration fueled by the potential clinical application of these antigens to clinical transplantation has advanced the field rapidly. There were nine inter- national histocompatibility workshops held during this period. Although iden- tification of HLA antigens was of primary clinical importance in transplantation 2 and of great basic interest in human genetics and anthropology, a rather un- expected bonus has been the determination that HLA antigens are associated with disease susceptibility to a greater extent than any other known genetic marker in man | 出版日期 | Book 1985 | 關(guān)鍵詞 | Antigen; Chromosom; DNA; Retinoblastom; Termination; Xeroderma pigmentosum; asthma; genes; genetics; infectio | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4613-8545-5 | isbn_softcover | 978-1-4613-8547-9 | isbn_ebook | 978-1-4613-8545-5 | copyright | Springer-Verlag New York, Inc. 1985 |
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