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Ebola: Virology, Clinical Considerations, and Outbreak Response and Prevention,It is caused by infection with one of the ebolaviruses, harbored within a yet undiscovered reservoir in West, Central, and East Africa. Here we review Ebola’s viral characteristics and pathogenesis; clinical considerations for diagnosis, treatment, and care of survivors; and finally, management and

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A Clinical Approach to Novel Diagnostics and Therapeutics: The Challenge of Zika,oms such as fever, headache, and myalgia. More specific symptoms include arthralgia in small joints, a maculopapular rash, and conjunctivitis. Zika-associated complications include Guillain-Barré syndrome and microcephaly. In this chapter, current and advanced diagnostic methods are discussed, inclu

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Hepatitis C Virus Infection in People Who Inject Drugs,ating hepatitis C in people who inject drugs benefits (1) the individual by improving health and preventing complications and (2) community health by preventing ongoing transmission to others. Hepatitis C treatment is proven to be effective in people with recent or active injection drug use, yet onl

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Hepatitis C: Updates in Epidemiology and for Treatment with Direct-Acting Antivirals,ocellular carcinoma. Since 2013, direct-acting antivirals have revolutionized HCV care. Older therapies were poorly tolerated and had limited efficacy; current therapies are well tolerated and cure the vast majority of patients who initiate them and remain adherent. Widespread HCV screening, impleme

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NeuroAIDS, Comorbid Mood Disorders and Neuropsychiatric Effects of Antiretroviral Therapy,ons living with HIV(PLWH) are a major health concern. HIV has been shown to directly affect the central and peripheral nervous system, leading to neurocognitive disorders collectively termed NeuroAIDS. In addition to the virus’ direct impacts on the brain, the medications used in the treatment of HI

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Marijuana and HIV,d for its medicinal properties for centuries. Marijuana is the most used of all illicit substances. Marijuana use is more common among people living with HIV/AIDS (PLWH) than the general population. It has been shown to have some therapeutic effects in PLWH, including stimulating appetite, reducing

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Mpox: An Emerging Global Orthopoxvirus Outbreak,t human case was reported in 1970. The disease has now gained notoriety since a global outbreak occurred in 2022–2023 (Monkeypox. .. Accessed 10 Sept 2023). Mpox can spread by direct and zoonotic transmission. The reemergence of MPXV was noted after the end of the smallpox vaccination era in 1980 (M

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Community-Acquired Respiratory Infections in HCT and Immunosuppressed Patients,. The best approach is preventing infection followed by timely microbiologically based polymerase chain reaction (PCR) testing to assess which patients require droplet isolation. In terms of therapy, influenza is the only respiratory infection with an FDA-approved therapy, oseltamivir.